4LHO

Crystal Structure of FG41Malonate Semialdehyde Decarboxylase inhibited by 3-bromopropiolate

Summary for 4LHO

Entry DOI	10.2210/pdb4lho/pdb
Descriptor	FG41 Malonate Semialdehyde Decarboxylase, 3-chloro-3-oxopropanoic acid, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	the tautomerase superfamily, beta-alpha-beta-motif, malonate semialdehyde decarboxylase, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
Biological source	coryneform bacterium
Total number of polymer chains	5
Total formula weight	74848.85
Authors	Guo, Y.,Serrano, H.,Poelarends, G.J.,Johnson Jr., W.H.,Hackert, M.L.,Whitman, C.P. (deposition date: 2013-07-01, release date: 2013-07-24, Last modification date: 2024-04-03)
Primary citation	Guo, Y.,Serrano, H.,Poelarends, G.J.,Johnson, W.H.,Hackert, M.L.,Whitman, C.P. Kinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase Activities. Biochemistry, 52:4830-4841, 2013 Cited by PubMed: 23781927 DOI: 10.1021/bi400567a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.224 Å)

Structure validation