4YI3
Crystal structure of Gpb in complex with 4a
Summary for 4YI3
Entry DOI | 10.2210/pdb4yi3/pdb |
Descriptor | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, N-{[3-(biphenyl-4-yl)propanoyl]carbamoyl}-beta-D-glucopyranosylamine, ... (6 entities in total) |
Functional Keywords | alpha and beta protein, transferase |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98526.33 |
Authors | Kantsadi, A.L.,Chatzileontiadou, D.S.M.,Stravodimos, G.A.,Leonidas, D.D. (deposition date: 2015-02-27, release date: 2015-11-18, Last modification date: 2024-01-10) |
Primary citation | Kantsadi, A.L.,Parmenopoulou, V.,Bakalov, D.N.,Snelgrove, L.,Stravodimos, G.A.,Chatzileontiadou, D.S.,Manta, S.,Panagiotopoulou, A.,Hayes, J.M.,Komiotis, D.,Leonidas, D.D. Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N -( beta-D-glucopyranosyl) urea inhibitors. Curr Top Med Chem, 15:2373-2389, 2015 Cited by PubMed: 26088352DOI: 10.2174/1568026615666150619142253 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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