Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
3SR5
DownloadVisualize
BU of 3sr5 by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 7-(3,4-dimethoxyphenyl)-6-methylquinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-06
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SRW
DownloadVisualize
BU of 3srw by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 7-(2-ethoxynaphthalen-1-yl)-6-methylquinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-07
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3BUL
DownloadVisualize
BU of 3bul by Molmil
E. coli I690C/G743C MetH C-terminal fragment (649-1227)
分子名称: COBALAMIN, Methionine synthase
著者Koutmos, M, Pattridge, K.A, Ludwig, M.L.
登録日2008-01-03
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BXJ
DownloadVisualize
BU of 3bxj by Molmil
Crystal Structure of the C2-GAP Fragment of synGAP
分子名称: Ras GTPase-activating protein SynGAP
著者Pena, V, Hothorn, M, Eberth, A, Kaschau, N, Parret, A, Gremer, L, Bonneau, F, Ahmadian, M.R, Scheffzek, K.
登録日2008-01-14
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
Embo Rep., 9, 2008
3BOM
DownloadVisualize
BU of 3bom by Molmil
Crystal structure of trout hemoglobin at 1.35 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, Hemoglobin subunit alpha-4, Hemoglobin subunit beta-4, ...
著者Aranda IV, R, Bingman, C.A, Bitto, E, Wesenberg, G.E, Richards, M, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-12-17
公開日2008-01-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Trout Hemoglobin Crystal Structure at 1.35 Angstroms Resolution.
To be Published
3BPZ
DownloadVisualize
BU of 3bpz by Molmil
HCN2-I 443-460 E502K in the presence of cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Craven, K.B, Olivier, N.B, Zagotta, W.N.
登録日2007-12-19
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献C-terminal movement during gating in cyclic nucleotide-modulated channels.
J.Biol.Chem., 283, 2008
3C5I
DownloadVisualize
BU of 3c5i by Molmil
Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520
分子名称: CALCIUM ION, CHOLINE ION, Choline kinase, ...
著者Wernimont, A.K, Hills, T, Lew, J, Wasney, G, Senesterra, G, Kozieradzki, I, Cossar, D, Vedadi, M, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Xiao, T, Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520.
To be Published
3BT7
DownloadVisualize
BU of 3bt7 by Molmil
Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue
分子名称: RNA (5'-D(P*GP*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*CP*CP*AP*CP*AP*GP*C)-3'), tRNA (uracil-5-)-methyltransferase
著者Alian, A, Stroud, R.M, Finer-Moore, J.
登録日2007-12-27
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BUX
DownloadVisualize
BU of 3bux by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met
分子名称: 13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3POX
DownloadVisualize
BU of 3pox by Molmil
Crystal Structure of E.coli OmpF porin in lipidic cubic phase: space group P1
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OmpF protein, POTASSIUM ION, ...
著者Efremov, R.G, Sazanov, L.A.
登録日2010-11-23
公開日2012-03-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Escherichia coli OmpF porin from lipidic mesophase.
J.Struct.Biol., 178, 2012
3C3N
DownloadVisualize
BU of 3c3n by Molmil
Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y
分子名称: Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Pinheiro, M.P, Iulek, J, Nonato, M.C.
登録日2008-01-28
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain
Biochem.Biophys.Res.Commun., 369, 2008
3C61
DownloadVisualize
BU of 3c61 by Molmil
Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, AZIDE ION, CHLORIDE ION, ...
著者Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2008-02-01
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dihydroorotate dehydrogenase from Leishmania donovani.
To be Published
3C1E
DownloadVisualize
BU of 3c1e by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS L125K at cryogenic temperature
分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
著者Khangulov, V.S, Schlessman, J.L, Garcia-Moreno, E.B.
登録日2008-01-23
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Staphylococcal nuclease variant Delta+PHS L125K at cryogenic temperature
To be Published
3BUM
DownloadVisualize
BU of 3bum by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2
分子名称: E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2
著者Ng, C, Jackson, A.R, Buschdorf, P.J, Sun, Q, Guy, R.G, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUW
DownloadVisualize
BU of 3buw by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk
分子名称: 13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL
著者Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BWY
DownloadVisualize
BU of 3bwy by Molmil
Crystal Structure of Human 108M Catechol O-methyltransferase bound with S-adenosylmethionine and inhibitor dinitrocatechol
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3,5-DINITROCATECHOL, COMT protein, ...
著者Rutherford, K, Le Trong, I, Stenkamp, R.E, Parson, W.W.
登録日2008-01-10
公開日2008-06-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of human 108V and 108M catechol O-methyltransferase.
J.Mol.Biol., 380, 2008
3BY8
DownloadVisualize
BU of 3by8 by Molmil
Crystal Structure of the E.coli DcuS Sensor Domain
分子名称: (2S)-2-hydroxybutanedioic acid, Sensor protein dcuS
著者Cheung, J, Hendrickson, W.A.
登録日2008-01-15
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structures of C4-Dicarboxylate Ligand Complexes with Sensor Domains of Histidine Kinases DcuS and DctB.
J.Biol.Chem., 283, 2008
3BZ3
DownloadVisualize
BU of 3bz3 by Molmil
Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor
分子名称: Focal adhesion kinase 1, N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide
著者Vajdos, F, Marr, E.
登録日2008-01-17
公開日2008-04-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271.
Cancer Res., 68, 2008
2ZSX
DownloadVisualize
BU of 2zsx by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser on [600 min]
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
登録日2008-09-18
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin.
Proc.Natl.Acad.Sci.USA, 106, 2009
3TDB
DownloadVisualize
BU of 3tdb by Molmil
Human Pin1 bound to trans peptidomimetic inhibitor
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, N-[(1E,2R)-1-[(2R)-2-{[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}cyclopentylidene]-3-(phosphonooxy)propan-2-yl]-L-phenylalaninamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Zhang, M, Zhang, Y.
登録日2011-08-10
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.267 Å)
主引用文献Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code.
Acs Chem.Biol., 7, 2012
2ZGG
DownloadVisualize
BU of 2zgg by Molmil
Asn-hydroxylation stabilises the ankyrin repeat domain fold
分子名称: 3 repeat synthetic ankyrin, CADMIUM ION, COBALT (II) ION
著者McDonough, M.A, Schofield, C.J.
登録日2008-01-21
公開日2008-02-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold
Mol Biosyst, 5, 2009
2ZKM
DownloadVisualize
BU of 2zkm by Molmil
Crystal Structure of Phospholipase C Beta 2
分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2, CALCIUM ION
著者Hicks, S.N, Jezyk, M.R, Gershberg, S, Seifert, J.P, Harden, T.K, Sondek, J.
登録日2008-03-26
公開日2008-08-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献General and versatile autoinhibition of PLC isozymes
Mol.Cell, 31, 2008
3TFB
DownloadVisualize
BU of 3tfb by Molmil
Transthyretin natural mutant A25T
分子名称: Transthyretin
著者Azevedo, E.P.C, Pereira, H.M, Garratt, R.C, Kelly, J.W, Foguel, D, Palhano, F.L.
登録日2011-08-15
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.033 Å)
主引用文献Dissecting the Structure, Thermodynamic Stability, and Aggregation Properties of the A25T Transthyretin (A25T-TTR) Variant Involved in Leptomeningeal Amyloidosis: Identifying Protein Partners That Co-Aggregate during A25T-TTR Fibrillogenesis in Cerebrospinal Fluid.
Biochemistry, 50, 2011
2ZST
DownloadVisualize
BU of 2zst by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser on [450 min]
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
登録日2008-09-17
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin.
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZT2
DownloadVisualize
BU of 2zt2 by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 120 K: Laser on [600 min]
分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
登録日2008-09-18
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin
Proc.Natl.Acad.Sci.USA, 106, 2009

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon