3BXJ
Crystal Structure of the C2-GAP Fragment of synGAP
Summary for 3BXJ
Entry DOI | 10.2210/pdb3bxj/pdb |
Descriptor | Ras GTPase-activating protein SynGAP (1 entity in total) |
Functional Keywords | gtpase activating protein, gtpase activation, membrane, phosphoprotein, sh3-binding, signaling protein |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Membrane; Peripheral membrane protein: Q9QUH6 |
Total number of polymer chains | 2 |
Total formula weight | 108890.97 |
Authors | Pena, V.,Hothorn, M.,Eberth, A.,Kaschau, N.,Parret, A.,Gremer, L.,Bonneau, F.,Ahmadian, M.R.,Scheffzek, K. (deposition date: 2008-01-14, release date: 2008-03-25, Last modification date: 2024-02-21) |
Primary citation | Pena, V.,Hothorn, M.,Eberth, A.,Kaschau, N.,Parret, A.,Gremer, L.,Bonneau, F.,Ahmadian, M.R.,Scheffzek, K. The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. Embo Rep., 9:350-355, 2008 Cited by PubMed: 18323856DOI: 10.1038/embor.2008.20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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