3TFB
Transthyretin natural mutant A25T
Summary for 3TFB
Entry DOI | 10.2210/pdb3tfb/pdb |
Descriptor | Transthyretin (2 entities in total) |
Functional Keywords | transthyretin, immunoglobulin-like, transport protein, extracellular, hormone-binding protein, hormone binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 25466.49 |
Authors | Azevedo, E.P.C.,Pereira, H.M.,Garratt, R.C.,Kelly, J.W.,Foguel, D.,Palhano, F.L. (deposition date: 2011-08-15, release date: 2011-12-07, Last modification date: 2023-09-13) |
Primary citation | Azevedo, E.P.,Pereira, H.M.,Garratt, R.C.,Kelly, J.W.,Foguel, D.,Palhano, F.L. Dissecting the Structure, Thermodynamic Stability, and Aggregation Properties of the A25T Transthyretin (A25T-TTR) Variant Involved in Leptomeningeal Amyloidosis: Identifying Protein Partners That Co-Aggregate during A25T-TTR Fibrillogenesis in Cerebrospinal Fluid. Biochemistry, 50:11070-11083, 2011 Cited by PubMed: 22091638DOI: 10.1021/bi201365r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.033 Å) |
Structure validation
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