7Q97
| Structure of the bacterial type VI secretion system effector RhsA. | 分子名称: | Rhs family protein | 著者 | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | 登録日 | 2021-11-12 | 公開日 | 2021-12-22 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of a bacterial Rhs effector exported by the type VI secretion system. Plos Pathog., 18, 2022
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2RK2
| DHFR R-67 complexed with NADP | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Dihydrofolate reductase type 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Krahn, J.M, London, R.E. | 登録日 | 2007-10-16 | 公開日 | 2008-06-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a type II dihydrofolate reductase catalytic ternary complex. Biochemistry, 46, 2007
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6H6E
| PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3) | 分子名称: | TcdA1, TcdB2,TccC3 | 著者 | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | 登録日 | 2018-07-27 | 公開日 | 2018-10-03 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Tc toxin activation requires unfolding and refolding of a beta-propeller. Nature, 563, 2018
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7QE0
| 80S-bound human SKI complex in the open state | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QLA
| Structure of the Rab GEF complex Mon1-Ccz1 | 分子名称: | Ccz1, Vacuolar fusion protein MON1 | 著者 | Klink, B.U, Herrmann, E, Antoni, C, Langemeyer, L, Kiontke, S, Gatsogiannis, C, Ungermann, C, Raunser, S, Kuemmel, D. | 登録日 | 2021-12-20 | 公開日 | 2022-02-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7QDS
| Apo human SKI complex in the open state | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | 著者 | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | 登録日 | 2021-11-30 | 公開日 | 2022-02-02 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDZ
| 80S-bound human SKI complex in the closed state | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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6GF2
| The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome | 分子名称: | Ubiquitin D | 著者 | Aichem, A, Anders, S, Catone, N, Roessler, P, Stotz, S, Berg, A, Schwab, R, Scheuermann, S, Bialas, J, Schmidtke, G, Peter, C, Groettrup, M, Wiesner, S. | 登録日 | 2018-04-29 | 公開日 | 2018-08-08 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation. Nat Commun, 9, 2018
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7QDR
| Apo human SKI complex in the closed state | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-11-29 | 公開日 | 2022-02-02 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QIO
| Homology model of myosin neck domain in skeletal sarcomere | 分子名称: | Myosin light chain 1/3, skeletal muscle isoform, Myosin regulatory light chain 2, ... | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | 登録日 | 2021-12-15 | 公開日 | 2022-02-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
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7QDY
| RNA-bound human SKI complex | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QIN
| In situ structure of actomyosin complex in skeletal sarcomere | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | 登録日 | 2021-12-15 | 公開日 | 2022-02-16 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
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7QPG
| Human RZZ kinetochore corona complex. | 分子名称: | Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog | 著者 | Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A. | 登録日 | 2022-01-04 | 公開日 | 2022-03-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. Embo J., 41, 2022
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6YU9
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6YUZ
| Homodimeric structure of the rBAT complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT | 著者 | Wu, D, Safarian, S, Michel, H. | 登録日 | 2020-04-27 | 公開日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proc.Natl.Acad.Sci.USA, 117, 2020
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6HFB
| Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily. | 分子名称: | CESIUM ION, Uncharacterized protein | 著者 | Nonaka, T, Zakrzewska, S, Safarian, S, Michel, H. | 登録日 | 2018-08-21 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.495 Å) | 主引用文献 | Inward-facing conformation of a multidrug resistance MATE family transporter. Proc.Natl.Acad.Sci.USA, 116, 2019
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7QP6
| Structure of the human 48S initiation complex in open state (h48S AUG open) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. | 登録日 | 2022-01-03 | 公開日 | 2022-05-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
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7QP7
| Structure of the human 48S initiation complex in closed state (h48S AUG closed) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. | 登録日 | 2022-01-03 | 公開日 | 2022-05-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
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6YUP
| Heterotetrameric structure of the rBAT-b(0,+)AT1 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT, ... | 著者 | Wu, D, Safarian, S, Michel, H. | 登録日 | 2020-04-27 | 公開日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proc.Natl.Acad.Sci.USA, 117, 2020
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2V2Q
| IspE in complex with ligand | 分子名称: | 4-AMINO-1-(5-{[3-(1H-BENZIMIDAZOL-2-YL)PROPANOYL]AMINO}-5-DEOXY-ALPHA-L-LYXOFURANOSYL)PYRIMIDIN-2(1H)-ONE, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, BROMIDE ION, ... | 著者 | Alphey, M.S, Hunter, W.N. | 登録日 | 2007-06-06 | 公開日 | 2007-06-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase Ispe of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis. Chemmedchem, 3, 2008
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7QH2
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6HR7
| HMG-CoA reductase from Methanothermococcus thermolithotrophicus apo form at 2.4 A resolution | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... | 著者 | Wagner, T, Voegeli, B, Erb, T.J, Shima, S. | 登録日 | 2018-09-26 | 公開日 | 2019-02-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme. Febs Lett., 593, 2019
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6HUZ
| HmdII from Desulfurobacterium thermolithotrophum reconstituted with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form B | 分子名称: | 1,2-ETHANEDIOL, 5,10-Methenyltetrahydrofolate, Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein, ... | 著者 | Watanabe, T, Wagner, T, Huang, G, Kahnt, J, Ataka, K, Ermler, U, Shima, S. | 登録日 | 2018-10-09 | 公開日 | 2019-01-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates. Angew. Chem. Int. Ed. Engl., 58, 2019
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6HUY
| HmdII from Desulfurobacterium thermolithotrophum reconstitued with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form A | 分子名称: | 5,10-Methenyltetrahydrofolate, Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein, DIMETHYL SULFOXIDE, ... | 著者 | Watanabe, T, Wagner, T, Huang, G, Kahnt, J, Ataka, K, Ermler, U, Shima, S. | 登録日 | 2018-10-09 | 公開日 | 2019-01-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates. Angew. Chem. Int. Ed. Engl., 58, 2019
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6HAC
| Crystal structure of [Fe]-hydrogenase (Hmd) holoenzyme from Methanococcus aeolicus (open form) | 分子名称: | 5,10-methenyltetrahydromethanopterin hydrogenase, GLYCEROL, PENTAETHYLENE GLYCOL, ... | 著者 | Huang, G, Wagner, T, Wodrich, M.D, Ataka, K, Bill, E, Ermler, U, Hu, X, Shima, S. | 登録日 | 2018-08-07 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The atomic-resolution crystal structure of activated [Fe]-hydrogenase Nat Catal, 2019
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