6GF2

The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome

Summary for 6GF2

• Entry DOI: 10.2210/pdb6gf2/pdb
• NMR Information: BMRB: 27466
• Descriptor: Ubiquitin D (1 entity in total)
• Functional Keywords: fat10, ubiquitin-like modifier, proteasome, degradation, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 9263.70

Authors

Aichem, A.,Anders, S.,Catone, N.,Roessler, P.,Stotz, S.,Berg, A.,Schwab, R.,Scheuermann, S.,Bialas, J.,Schmidtke, G.,Peter, C.,Groettrup, M.,Wiesner, S. (deposition date: 2018-04-29, release date: 2018-08-08, Last modification date: 2024-06-19)

• Primary citation: Aichem, A.,Anders, S.,Catone, N.,Stotz, S.,Berg, A.,Schwab, R.,Scheuermann, S.,Bialas, J.,Schutz-Stoffregen, M.C.,Schmidtke, G.,Peter, C.,Groettrup, M.,Wiesner, S.; The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.; Nat Commun, 9:3321-3321, 2018; PubMed: 30127417; DOI: 10.1038/s41467-018-05776-3

Experimental method

SOLUTION NMR