2W3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w3d by Molmil](/molmil-images/mine/2w3d) | |
1MZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mzg by Molmil](/molmil-images/mine/1mzg) | X-Ray Structure of SufE from E.coli Northeast Structural Genomics (NESG) Consortium Target ER30 | 分子名称: | SufE Protein | 著者 | Kuzin, A, Edstrom, W.C, Xiao, R, Acton, T.B, Rost, B, Tong, L, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-10-07 | 公開日 | 2003-01-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The SufE sulfur-acceptor protein contains a conserved core structure that mediates interdomain interactions in a variety of redox protein complexes J.Mol.Biol., 344, 2004
|
|
9BFB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9bfb by Molmil](/molmil-images/mine/9bfb) | Crystal structure of BRAF kinase domain with PF-07284890 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, N-{2-chloro-3-[(3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-fluorophenyl}-3-fluoropropane-1-sulfonamide, ... | 著者 | Mou, T.-C. | 登録日 | 2024-04-17 | 公開日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Identification of the Clinical Candidate PF-07284890 ( ARRY-461 ), a Highly Potent and Brain Penetrant BRAF Inhibitor for the Treatment of Cancer. J.Med.Chem., 67, 2024
|
|
2W3E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w3e by Molmil](/molmil-images/mine/2w3e) | |
3J9O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j9o by Molmil](/molmil-images/mine/3j9o) | CryoEM structure of a type VI secretion system | 分子名称: | Intracellular growth locus protein A, Intracellular growth locus protein B | 著者 | Clemens, D.L, Ge, P, Lee, B.-Y, Horwitz, M.A, Zhou, Z.H. | 登録日 | 2015-02-11 | 公開日 | 2015-03-18 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Atomic Structure of T6SS Reveals Interlaced Array Essential to Function. Cell(Cambridge,Mass.), 160, 2015
|
|
3JV5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jv5 by Molmil](/molmil-images/mine/3jv5) | |
4QCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qci by Molmil](/molmil-images/mine/4qci) | PDGF-B blocking antibody bound to PDGF-BB | 分子名称: | Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain | 著者 | Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G. | 登録日 | 2014-05-12 | 公開日 | 2015-03-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta. Biochemistry, 54, 2015
|
|
3Q14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q14 by Molmil](/molmil-images/mine/3q14) | Toluene 4 monooxygenase HD Complex with p-cresol | 分子名称: | FE (III) ION, P-CRESOL, PENTAETHYLENE GLYCOL, ... | 著者 | Acheson, J.F, Bailey, L.J, Fox, B.G. | 登録日 | 2010-12-16 | 公開日 | 2011-12-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
|
|
5UQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uqe by Molmil](/molmil-images/mine/5uqe) | Multidomain structure of human kidney-type glutaminase(KGA/GLS) | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | 著者 | Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B. | 登録日 | 2017-02-08 | 公開日 | 2017-05-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. J. Biol. Chem., 292, 2017
|
|
1BWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bwn by Molmil](/molmil-images/mine/1bwn) | PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT E41K IN COMPLEX WITH INS(1,3,4,5)P4 | 分子名称: | BRUTON'S TYROSINE KINASE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ZINC ION | 著者 | Djinovic Carugo, K, Baraldi, E, Hyvoenen, M, Lo Surdo, P, Riley, A, Potter, B, Saraste, M. | 登録日 | 1998-09-25 | 公開日 | 1999-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. Structure Fold.Des., 7, 1999
|
|
2NZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nz5 by Molmil](/molmil-images/mine/2nz5) | Structure and Function Studies of Cytochrome P450 158A1 from Streptomyces coelicolor A3(2) | 分子名称: | Cytochrome P450 CYP158A1, PROTOPORPHYRIN IX CONTAINING FE, naphthalene-1,2,4,5,7-pentol | 著者 | Zhao, B, Lamb, D.C, Kelly, S.L, Waterman, M.R. | 登録日 | 2006-11-22 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2. Biochemistry, 46, 2007
|
|
2V9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v9b by Molmil](/molmil-images/mine/2v9b) | X-ray structure of viscotoxin B2 from Viscum album | 分子名称: | SULFATE ION, VISCOTOXIN-B | 著者 | Debreczeni, J.E, Pal, A, Kahle, B, Zeeck, A, Sheldrick, G.M. | 登録日 | 2007-08-23 | 公開日 | 2008-06-17 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Structures of viscotoxins A1 and B2 from European mistletoe solved using native data alone. Acta Crystallogr. D Biol. Crystallogr., 64, 2008
|
|
1CGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cgx by Molmil](/molmil-images/mine/1cgx) | |
2V2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v2t by Molmil](/molmil-images/mine/2v2t) | X-ray structure of a NF-kB p50-RelB-DNA complex | 分子名称: | 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3', NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, TRANSCRIPTION FACTOR RELB | 著者 | Moorthy, A.K, Huang, D.B, Wang, V.Y, Vu, D, Ghosh, G. | 登録日 | 2007-06-07 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | X-Ray Structure of a NF-kappaB p50/Relb/DNA Complex Reveals Assembly of Multiple Dimers on Tandem kappaB Sites. J.Mol.Biol., 373, 2007
|
|
1K3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k3z by Molmil](/molmil-images/mine/1k3z) | X-ray crystal structure of the IkBb/NF-kB p65 homodimer complex | 分子名称: | Transcription factor p65, transcription factor inhibitor I-kappa-B-beta | 著者 | Shiva, M, Huang, D.B, Chen, Y, Huxford, T, Ghosh, S, Ghosh, G. | 登録日 | 2001-10-04 | 公開日 | 2002-10-04 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex. J.Biol.Chem., 278, 2003
|
|
1JCT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jct by Molmil](/molmil-images/mine/1jct) | Glucarate Dehydratase, N341L mutant Orthorhombic Form | 分子名称: | D-GLUCARATE, Glucarate Dehydratase, ISOPROPYL ALCOHOL, ... | 著者 | Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. | 登録日 | 2001-06-11 | 公開日 | 2001-09-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli. Biochemistry, 40, 2001
|
|
1JDZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jdz by Molmil](/molmil-images/mine/1jdz) | CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE WITH FORMYCIN B AND SULFATE ION | 分子名称: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, FORMYCIN B, SULFATE ION | 著者 | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | 登録日 | 2001-06-15 | 公開日 | 2001-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
|
|
4IF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4if8 by Molmil](/molmil-images/mine/4if8) | Structure Of Vaspin | 分子名称: | SULFATE ION, Serpin A12 | 著者 | Kuettner, E.B, Strater, N, Heiker, J.T, Kloting, N, Kovacs, P, Schultz, S, Kern, M, Stumvoll, M, Bluher, M, Beck-Sickinger, A.G. | 登録日 | 2012-12-14 | 公開日 | 2013-02-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Vaspin inhibits kallikrein 7 by serpin mechanism Cell.Mol.Life Sci., 70, 2013
|
|
1XL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xl0 by Molmil](/molmil-images/mine/1xl0) | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. | 分子名称: | (1R)-1,5-anhydro-1-(5-methyl-1,3,4-oxadiazol-2-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ... | 著者 | Chrysina, E.D, Kosmopoulou, M.N, Tiraidis, C, Kardakaris, R, Bischler, N, Leonidas, D.D, Hadady, Z, Somsak, L, Docsa, T, Gergely, P, Oikonomakos, N.G. | 登録日 | 2004-09-30 | 公開日 | 2005-03-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site Protein Sci., 14, 2005
|
|
6IAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iah by Molmil](/molmil-images/mine/6iah) | Phosphatase Tt82 from Thermococcus thioreducens | 分子名称: | CHLORIDE ION, Hydrolase, MAGNESIUM ION | 著者 | Havlickova, P, Brinsa, V, Brynda, J, Pachl, P, Prudnikova, T, Mesters, J.R, Kascakova, B, Kuty, M, Pusey, M.L, Ng, J.D, Rezacova, P, Smatanova, I.K. | 登録日 | 2018-11-26 | 公開日 | 2019-08-14 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A novel structurally characterized haloacid dehalogenase superfamily phosphatase from Thermococcus thioreducens with diverse substrate specificity. Acta Crystallogr D Struct Biol, 75, 2019
|
|
5D85
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d85 by Molmil](/molmil-images/mine/5d85) | Staphyloferrin B precursor biosynthetic enzyme SbnA bound to aminoacrylate intermediate | 分子名称: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CITRATE ANION, GLYCEROL, ... | 著者 | Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. | 登録日 | 2015-08-15 | 公開日 | 2016-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
|
|
1D90
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1d90 by Molmil](/molmil-images/mine/1d90) | REFINED CRYSTAL STRUCTURE OF AN OCTANUCLEOTIDE DUPLEX WITH I.T MISMATCHED BASE PAIRS | 分子名称: | DNA (5'-D(*GP*GP*IP*GP*CP*TP*CP*C)-3') | 著者 | Cruse, W.B.T, Aymani, J, Kennard, O, Brown, T, Jack, A.G.C, Leonard, G.A. | 登録日 | 1992-10-17 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs. Nucleic Acids Res., 17, 1989
|
|
1XL1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xl1 by Molmil](/molmil-images/mine/1xl1) | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. | 分子名称: | (1R)-1,5-anhydro-1-(5-methyl-1,3-benzothiazol-2-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ... | 著者 | Chrysina, E.D, Kosmopoulou, M.N, Tiraidis, C, Kardakaris, R, Bischler, N, Leonidas, D.D, Hadady, Z, Somsak, L, Docsa, T, Gergely, P, Oikonomakos, N.G. | 登録日 | 2004-09-30 | 公開日 | 2005-03-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site Protein Sci., 14, 2005
|
|
1CGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cgw by Molmil](/molmil-images/mine/1cgw) | |
1KJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kj3 by Molmil](/molmil-images/mine/1kj3) | Mhc Class I H-2Kb molecule complexed with pKB1 peptide | 分子名称: | BETA-2 MICROGLOBULIN, H-2KB MHC CLASS I MOLECULE ALPHA CHAIN, NATURALLY PROCESSED OCTAPEPTIDE PKB1 | 著者 | Reiser, J.-B, Gregoire, C, Darnault, C, Mosser, T, Guimezanes, A, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Mazza, G, Malissen, B, Housset, D. | 登録日 | 2001-12-04 | 公開日 | 2002-03-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex. Immunity, 16, 2002
|
|