1BWN

PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT E41K IN COMPLEX WITH INS(1,3,4,5)P4

Summary for 1BWN
DescriptorBRUTON'S TYROSINE KINASE, ZINC ION, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... (4 entities in total)
Functional Keywordstransferase, ph domain, btk motif, inositol-(1, 3, 4, 5)-tetrakisphosphate, zinc binding, x-linked agammaglobulinemia, tyrosine-protein kinase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity): Q06187
Total number of polymer chains2
Total formula weight42097.27
Authors
Djinovic Carugo, K.,Baraldi, E.,Hyvoenen, M.,Lo Surdo, P.,Riley, A.,Potter, B.,Saraste, M. (deposition date: 1998-09-25, release date: 1999-06-15, Last modification date: 2011-07-13)
Primary citationBaraldi, E.,Carugo, K.D.,Hyvonen, M.,Ladbury, J.E.,O'Brien, R.,Potter, B.V.,Riley, A.M.,Saraste, M.,Surdo, P.L.
Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.
Structure Fold.Des., 7:449-460, 1999
PubMed: 10196129
DOI: 110.1016/S0969-2126(99)80057-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation
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PDB entries from 2021-06-09