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8EK4
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De novo designed ice-binding proteins from twist-constrained helices
分子名称: Ice-binding protein TIP-99a
著者Bera, A.K, De Haas, R.J.
登録日2022-09-19
公開日2023-07-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献De novo designed ice-binding proteins from twist-constrained helices.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EK3
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Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-19
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EK1
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Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
分子名称: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
著者Tripathi, P, Kwong, P.D.
登録日2022-09-19
公開日2023-03-15
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8EJN
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Structure of dehaloperoxidase A in complex with 2,4-dichlorophenol
分子名称: 2,4-dichlorophenol, DIMETHYL SULFOXIDE, Dehaloperoxidase A, ...
著者Aktar, M.S, de Serrano, V.S, Franzen, S.
登録日2022-09-17
公開日2023-08-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.481 Å)
主引用文献Comparative study of the binding and activation of 2,4-dichlorophenol by dehaloperoxidase A and B.
J.Inorg.Biochem., 247, 2023
8EJM
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Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DHX15, CHLORIDE ION, ...
著者Huang, J, Tong, L.
登録日2022-09-17
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EJJ
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Lassa virus glycoprotein complex (Josiah) bound to S370.7 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJI
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Lassa virus glycoprotein complex (Josiah) bound to 19.7E Fab
分子名称: 19.7E Fab heavy chain, 19.7E Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJH
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Lassa virus glycoprotein complex (Josiah) bound to 12.1F Fab
分子名称: 12.1F Fab heavy chain, 12.1F Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJG
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Structure of lineage VII Lassa virus glycoprotein complex (strain Togo/2016/7082)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJF
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Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJE
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Structure of lineage II Lassa virus glycoprotein complex (strain NIG08-A41)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJD
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Structure of lineage IV Lassa virus glycoprotein complex (strain Josiah)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJ8
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Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAAAGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), GLYCEROL, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-16
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EJ7
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BU of 8ej7 by Molmil
Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates
分子名称: 3C-like proteinase nsp5
著者Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J.
登録日2022-09-16
公開日2023-05-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Acs Cent.Sci., 9, 2023
8EJ6
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Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-16
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EJ4
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Cryo-EM structure of the active NLRP3 inflammasome disk
分子名称: MAGNESIUM ION, NACHT, LRR and PYD domains-containing protein 3, ...
著者Hao, W, Le, X.
登録日2022-09-16
公開日2022-12-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of the active NLRP3 inflammasome disc.
Nature, 613, 2023
8EJ0
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Crystal structure of Fe-S cluster-dependent dehydratase from Paralcaligenes ureilyticus in complex with Mg
分子名称: BICARBONATE ION, CARBON DIOXIDE, Dihydroxyacid dehydratase, ...
著者Bayaraa, T, Lonhienne, T, Guddat, L.W.
登録日2022-09-16
公開日2023-08-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structure of Fe-S cluster-dependent dehydratase from Paralcaligenes ureilyticus in complex with Mg
To Be Published
8EIZ
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BU of 8eiz by Molmil
Cryo-EM structure of squid sensory receptor CRB1
分子名称: N-benzyl-2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium, Squid sensory receptor CRB1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Kang, G, Kim, J.J, Allard, C.A.H, Valencia-Montoya, W.A, van Giesen, L, Kilian, P.B, Bai, X, Bellono, N.W, Hibbs, R.E.
登録日2022-09-15
公開日2023-04-12
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Sensory specializations drive octopus and squid behaviour.
Nature, 616, 2023
8EIS
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Cryo-EM structure of octopus sensory receptor CRT1
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Octopus sensory receptor
著者Kang, G, Kim, J.J, Allard, C.A.H, Valencia-Montoya, W.A, Bellono, N.W, Hibbs, R.E.
登録日2022-09-15
公開日2023-04-12
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Sensory specializations drive octopus and squid behaviour.
Nature, 616, 2023
8EIP
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Crystal structure of cyanophycin dipeptide hydrolase CphZ E251A from Acinetobacter baylyi DSM587 in complex with beta-Asp-Arg
分子名称: (2~{S})-4-[[(2~{S})-5-[[azanyl($l^{4}-azanylidene)methyl]amino]-1-$l^{1}-oxidanyl-1-oxidanylidene-pentan-2-yl]amino]-2-$l^{2}-azanyl-4-oxidanylidene-butanoic acid, MANGANESE (II) ION, Succinylglutamate desuccinylase, ...
著者Sharon, I, Schmeing, T.M.
登録日2022-09-15
公開日2023-03-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EIO
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The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with elexacaftor (VX-445), lumacaftor (VX-809) and ATP/Mg
分子名称: (6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ...
著者Fiedorczuk, K, Chen, J.
登録日2022-09-15
公開日2022-10-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular structures reveal synergistic rescue of Delta 508 CFTR by Trikafta modulators.
Science, 378, 2022
8EIN
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Crystal structure of WT cyanophycin dipeptide hydrolase CphZ from Acinetobacter baylyi DSM587
分子名称: MANGANESE (II) ION, Succinylglutamate desuccinylase, ZINC ION
著者Sharon, I, Schmeing, T.M.
登録日2022-09-15
公開日2023-03-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EIM
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Structure of ALAS with C-terminal truncation from S. cerevisiae
分子名称: 5-aminolevulinate synthase, mitochondrial, ACETATE ION, ...
著者Tran, J.U, Brown, B.L.
登録日2022-09-15
公開日2023-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The yeast ALA synthase C-terminus positively controls enzyme structure and function.
Protein Sci., 32, 2023
8EIL
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C-Terminal Domain of BrxL from Acinetobacter BREX type I phage restriction system
分子名称: MALONIC ACID, Protease Lon-related BREX system protein BrxL, SUCCINIC ACID
著者Doyle, L.A, Stoddard, B.L, Kaiser, B.
登録日2022-09-15
公開日2023-02-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor.
Nucleic Acids Res., 51, 2023
8EIF
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Crystal structure of unmodified Pseudomonas aeruginosa protein PA0709
分子名称: Antibiotic biosynthesis monooxygenase, CACODYLIC ACID, GLYCEROL, ...
著者Cuthbert, B.J, Goulding, C.W.
登録日2022-09-14
公開日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of PA0709
To Be Published

222415

件を2024-07-10に公開中

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