8EJM
Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
Summary for 8EJM
Entry DOI | 10.2210/pdb8ejm/pdb |
Descriptor | ATP-dependent RNA helicase DHX15, SURP and G-patch domain-containing protein 1, ADENOSINE-5'-DIPHOSPHATE, ... (8 entities in total) |
Functional Keywords | complex, helicase, splicing factor, rna binding protein, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 87723.13 |
Authors | |
Primary citation | Zhang, J.,Huang, J.,Xu, K.,Xing, P.,Huang, Y.,Liu, Z.,Tong, L.,Manley, J.L. DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer. Proc.Natl.Acad.Sci.USA, 119:e2216712119-e2216712119, 2022 Cited by PubMed: 36459648DOI: 10.1073/pnas.2216712119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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