8EJM
Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-dependent RNA helicase DHX15 | polymer | 686 | 78730.4 | 1 | UniProt (O43143) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) | Homo sapiens (human) | ATP-dependent RNA helicase #46,DEAH box protein 15,Splicing factor Prp43,hPrp43 |
| 2 | B (B) | SURP and G-patch domain-containing protein 1 | polymer | 74 | 8094.0 | 1 | UniProt (Q8IWZ8) Pfam (PF01585) | Homo sapiens (human) | RNA-binding protein RBP,Splicing factor 4 |
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | G, H (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | I, J (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | K, L (A, B) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A: 113 - 795 (UniProt: O43143)
B: 543 - 614 (UniProt: Q8IWZ8)
| PDB | External Database | Details |
|---|---|---|
| Ser 110 | - | expression tag |
| Asn 111 | - | expression tag |
| Met 112 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 541 | - | expression tag |
| Asn 542 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86824.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 898.7 | |
| All* | Total formula weight | 87723.1 |
