PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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1E7K	Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment 分子名称: 15.5 KD RNA BINDING PROTEIN, RNA (5'-R(*GP*CP*CP*AP*AP*UP*GP*AP*GP*GP*UP*UP*UP* AP*UP*CP*CP*GP*AP*GP*G*C(-3') 著者 Vidovic, I, Nottrott, S, Harthmuth, K, Luhrmann, R, Ficner, R. 登録日 2000-08-29 公開日 2001-02-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment Mol.Cell, 6, 2000
1E7L	Endonuclease VII (EndoVII) N62D mutant from phage T4 分子名称: RECOMBINATION ENDONUCLEASE VII, SULFATE ION, ZINC ION 著者 Raaijmakers, H.C.A, Vix, O, Toro, I, Suck, D. 登録日 2000-08-29 公開日 2001-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Conformational Flexibility in T4 Endonuclease Vii Revealed by Crystallography: Implications for Substrate Binding and Cleavage J.Mol.Biol., 308, 2001
1E7M	ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES 分子名称: CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE 著者 Adams, M.J, Cosgrove, M.S, Gover, S. 登録日 2000-08-30 公開日 2000-12-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry, 39, 2000
1E7N	The N-terminal domain of beta-B2-crystallin resembles the putative ancestral homodimer 分子名称: BETA-CRYSTALLIN B2 著者 Clout, N.J, Basak, A, Wieligmann, K, Bateman, O.A, Jaenicke, R, Slingsby, C. 登録日 2000-08-31 公開日 2000-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The N-Terminal Domain of Betab2-Crystallin Resembles the Putative Ancestral Homodimer. J.Mol.Biol., 304, 2000
1E7O	A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS 分子名称: GLYCEROL, SPECTRIN ALPHA CHAIN 著者 Vega, M.C, Serrano, L. 登録日 2000-08-31 公開日 2003-05-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A Thermodynamic and Kinetic Analysis of the Folding Pathway of an SH3 Domain Entropically Stabilised by a Redesigned Hydrophobic Core J.Mol.Biol., 328, 2003
1E7P	QUINOL:FUMARATE REDUCTASE FROM WOLINELLA SUCCINOGENES 分子名称: DODECYL-BETA-D-MALTOSIDE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... 著者 Lancaster, C.R.D, Kroeger, A. 登録日 2000-09-01 公開日 2001-04-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Third Crystal Form of Wolinella Succinogenes Quinol:Fumarate Reductase Reveals Domain Closure at the Site of Fumarate Reduction Eur.J.Biochem., 268, 2001
1E7Q	GDP 4-keto-6-deoxy-D-mannose epimerase reductase S107A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... 著者 Rosano, C, Izzo, G, Bolognesi, M. 登録日 2000-09-07 公開日 2000-10-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
1E7R	GDP 4-keto-6-deoxy-D-mannose epimerase reductase Y136E 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... 著者 Rosano, C, Izzo, G, Bolognesi, M. 登録日 2000-09-07 公開日 2000-10-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
1E7S	GDP 4-keto-6-deoxy-D-mannose epimerase reductase K140R 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... 著者 Rosano, C, Zuccotti, S, Izzo, G, Bolognesi, M. 登録日 2000-09-07 公開日 2000-10-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
1E7U	Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine 分子名称: (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT 著者 Walker, E.H, Perisic, O, Ried, C, Stephens, L, Williams, R.L. 登録日 2000-09-08 公開日 2000-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
1E7V	Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine 分子名称: 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT 著者 Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L. 登録日 2000-09-08 公開日 2000-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol.Cell, 6, 2000
1E7W	One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes 分子名称: 1,2-ETHANEDIOL, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Gourley, D.G, Hunter, W.N. 登録日 2000-09-11 公開日 2001-09-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites. Nat.Struct.Biol., 8, 2001
1E7Y	ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES COMPLEXED WITH SUBSTRATE AND NADPH 分子名称: 6-O-phosphono-beta-D-glucopyranose, CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, ... 著者 Adams, M.J, Cosgrove, M.S, Gover, S. 登録日 2000-09-12 公開日 2000-12-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry, 39, 2000
1E7Z	Crystal structure of the EMAP2/RNA binding domain of the p43 protein from human aminoacyl-tRNA synthetase complex 分子名称: ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II, MERCURY (II) ION 著者 Pasqualato, S, Kerjan, P, Renault, L, Menetrey, J, Mirande, M, Cherfils, J. 登録日 2000-09-13 公開日 2000-11-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the Emapii Domain of Human Aminoacyl-tRNA Synthetase Complex Reveals Evolutionary Dimeric Mimicry Embo J., 20, 2001
1E80	Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133 分子名称: 4-amino-N-{(1R,8R,9R,13R)-16-(4-amino-2-methylpyrimidin-5-yl)-1-benzyl-8-(cyclohexylmethyl)-9-hydroxy-13-[(1S)-1-methylpropyl]-2,6,11,14-tetraoxo-3,7,12,15-tetraazahexadec-1-yl}piperidine-1-carboxamide, ENDOTHIAPEPSIN 著者 Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. 登録日 2000-09-15 公開日 2000-09-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Ph D Thesis, 1999
1E81	Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD61395 分子名称: (2S)-1-{[(2R)-1-{[(2S,3S)-1-cyclohexyl-3-hydroxy-4-(2-oxopyridin-1(2H)-yl)butan-2-yl]amino}-3-(methylsulfanyl)-1-oxopropan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl 4-aminopiperidine-1-carboxylate, ENDOTHIAPEPSIN 著者 Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. 登録日 2000-09-15 公開日 2000-10-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Thesis, 1999
1E82	Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601 分子名称: (2S)-1-{[(2R)-1-{[(2S,3R)-1-cyclohexyl-3-hydroxy-4-(pyridin-4-yloxy)butan-2-yl]amino}-3-(methylsulfanyl)-1-oxopropan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl 4-aminopiperidine-1-carboxylate, ENDOTHIAPEPSIN 著者 Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. 登録日 2000-09-15 公開日 2000-10-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Thesis, 1999
1E83	Cytochrome c' from Alcaligenes xylosoxidans - oxidized structure 分子名称: CYTOCHROME C', HEME C 著者 Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. 登録日 2000-09-15 公開日 2000-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
1E84	Cytochrome c' from Alcaligenes xylosoxidans - reduced structure 分子名称: CYTOCHROME C', HEME C 著者 Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. 登録日 2000-09-15 公開日 2000-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
1E85	Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with NO bound to proximal side of heme 分子名称: CYTOCHROME C', HEME C, NITRIC OXIDE 著者 Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. 登録日 2000-09-15 公開日 2000-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase. Embo J., 19, 2000
1E86	Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme 分子名称: CARBON MONOXIDE, CYTOCHROME C', HEME C 著者 Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. 登録日 2000-09-15 公開日 2000-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
1E87	Human CD69 - trigonal form 分子名称: EARLY ACTIVATION ANTIGEN CD69, GLYCEROL, ZINC ION 著者 Tormo, J. 登録日 2000-09-18 公開日 2000-09-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the C-Type Lectin-Like Domain from the Human Hematopoietic Cell Receptor Cd69 J.Biol.Chem., 276, 2001
1E88	Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FIBRONECTIN 著者 Pickford, A.R, Smith, S.P, Staunton, D, Boyd, J, Campbell, I.D. 登録日 2000-09-18 公開日 2000-10-09 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 The Hairpin Structure of the (6)F1(1)F2(2)F2 Fragment from Human Fibronectin Enhances Gelatin Binding Embo J., 20, 2001
1E89	ON THE MECHANISM OF CYANOGENESIS CATALYZED BY HYDROXYNITRILE LYASE FROM MANIHOT ESCULENTA. CRYSTAL STRUCTURE OF ACTIVE SITE MUTANT SER80ALA IN COMPLEX WITH ACETONE CYANOHYDRIN 分子名称: HYDROXYNITRILE LYASE 著者 Lauble, H, Miehlich, B, Foerster, S, Wajant, H, Effenberger, F. 登録日 2000-09-18 公開日 2001-08-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanistic Aspects of Cyanogenesis from Active-Site Mutant Ser80Ala of Hydroxynitrile Lyase from Manihot Esculenta in Complex with Acetone Cyanohydrin Protein Sci., 10, 2001
1E8A	The three-dimensional structure of human S100A12 分子名称: CALCIUM ION, S100A12 著者 Moroz, O.V, Antson, A.A, Murshudov, G.N, Maitland, N.J, Dodson, G.G, Wilson, K.S, Skibshoj, I, Lukanidin, E.M, Bronstein, I.B. 登録日 2000-09-18 公開日 2001-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Three-Dimensional Structure of Human S100A12 Acta Crystallogr.,Sect.D, 57, 2001

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