PDB: 35802 件ウェブページステータス検索Chemie searchBIRD

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5DJV	Crystal structure of human FPPS in complex with biaryl compound 8e 分子名称: 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-02 公開日 2015-10-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
5DJR	Crystal structure of human FPPS in complex with biaryl compound 6 分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-09-02 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
2RND	Structure of the N-terminal BARpeptide in DPC micelles 分子名称: Myc box-dependent-interacting protein 1 著者 Loew, C, Weininger, U, Balbach, J. 登録日 2007-12-16 公開日 2008-10-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers Biophys.J., 95, 2008
3HVC	Crystal structure of human p38alpha MAP kinase 分子名称: 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, Mitogen-activated protein kinase 14 著者 Perry, J.J, Tainer, J.A. 登録日 2009-06-15 公開日 2009-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses. J.Mol.Biol., 391, 2009
2RMY	Structure of the N-terminal BARpeptide in SDS micelles 分子名称: Myc box-dependent-interacting protein 1 著者 Loew, C, Weininger, U, Balbach, J. 登録日 2007-12-03 公開日 2008-10-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers Biophys.J., 95, 2008
7W3O	Crystal structure of human CYB5R3 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 soluble form 著者 Noda, N.N. 登録日 2021-11-25 公開日 2022-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3. Nat Commun, 13, 2022
8PK0	human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 分子名称: 16S rRNA + pre-H68-71 segment, 39S ribosomal protein L10, mitochondrial, ... 著者 Kummer, E, Nguyen, T.G, Ritter, C. 登録日 2023-06-23 公開日 2023-12-13 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome. Nat Commun, 14, 2023
7UQB	Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... 著者 Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. 登録日 2022-04-19 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.43 Å) 主引用文献 rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
7UOO	Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... 著者 Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. 登録日 2022-04-13 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.34 Å) 主引用文献 rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
7UQZ	Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... 著者 Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. 登録日 2022-04-20 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.44 Å) 主引用文献 rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
7V08	Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... 著者 Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. 登録日 2022-05-10 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.36 Å) 主引用文献 rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
3F0M	Crystal structure of radical D105N Synechocystis sp. PcyA 分子名称: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase 著者 Kohler, A.C, Gae, D.D. 登録日 2008-10-25 公開日 2009-10-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants. Biochemistry, 49, 2010
3F0L	Crystal structure of oxidized D105N Synechocystis sp. PcyA 分子名称: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase 著者 Kohler, A.C, Gae, D.D. 登録日 2008-10-25 公開日 2009-10-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants. Biochemistry, 49, 2010
5OOM	Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA 分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... 著者 Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. 登録日 2017-08-08 公開日 2017-09-13 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Structures of the human mitochondrial ribosome in native states of assembly. Nat. Struct. Mol. Biol., 24, 2017
8QU5	mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2 分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... 著者 Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. 登録日 2023-10-13 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.42 Å) 主引用文献 GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
5XJL	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1/D2/F/E/G from Human 分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Zhang, R. 登録日 2017-05-02 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly Cell, 146, 2011
3FWN	Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate 分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, ... 著者 Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. 登録日 2009-01-19 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism J.Struct.Biol., 169, 2010
4RSE	Crystal structure of RPE65 in complex with MB-001 and palmitate 分子名称: (1R)-3-amino-1-{3-[(2,6,6-trimethylcyclohex-1-en-1-yl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ... 著者 Kiser, P.D, Shi, W, Palczewski, K. 登録日 2014-11-07 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat.Chem.Biol., 11, 2015
4RSC	Crystal structure of RPE65 in complex with emixustat and palmitate 分子名称: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ... 著者 Kiser, P.D, Shi, W, Palczewski, K. 登録日 2014-11-07 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat.Chem.Biol., 11, 2015
4FXF	Structure of M2 pyruvate kinase in complex with phenylalanine 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Walkinshaw, M.D, Morgan, H.P. 登録日 2012-07-03 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation. Proc.Natl.Acad.Sci.USA, 110, 2013
6L3A	Cytochrome P450 107G1 (RapN) with everolimus 分子名称: Cytochrome P450, Everolimus, PROTOPORPHYRIN IX CONTAINING FE 著者 Km, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. 登録日 2019-10-10 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
4FXJ	Structure of M2 pyruvate kinase in complex with phenylalanine 分子名称: PHENYLALANINE, PHOSPHATE ION, Pyruvate kinase isozymes M1/M2 著者 Walkinshaw, M.D, Morgan, H.P. 登録日 2012-07-03 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation. Proc.Natl.Acad.Sci.USA, 110, 2013
6L39	Cytochrome P450 107G1 (RapN) 分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... 著者 Kim, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. 登録日 2019-10-10 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
7NND	Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 09 分子名称: 14-3-3 protein sigma, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-02-24 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Fragment-based exploration of the 14-3-3/Amot-p130 interface. Curr Res Struct Biol, 4, 2022
7NMX	Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 12 分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CALCIUM ION, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-02-23 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment-based exploration of the 14-3-3/Amot-p130 interface. Curr Res Struct Biol, 4, 2022

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