3ZFW
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![BU of 3zfw by Molmil](/molmil-images/mine/3zfw) | Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide | 分子名称: | KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 | 著者 | Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P. | 登録日 | 2012-12-12 | 公開日 | 2013-04-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Basis for Kinesin-1:Cargo Recognition. Science, 340, 2013
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6TP5
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![BU of 6tp5 by Molmil](/molmil-images/mine/6tp5) | Crystal structure of human Transmembrane prolyl 4-hydroxylase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Myllykoski, M, Sutinen, A, Koski, M.K, Kallio, J.P, Raasakka, A, Myllyharju, J, Wierenga, R.K, Koivunen, P. | 登録日 | 2019-12-12 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains. J.Biol.Chem., 296, 2020
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3MWH
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![BU of 3mwh by Molmil](/molmil-images/mine/3mwh) | The 1.4 Ang crystal structure of the ArsD arsenic metallochaperone provides insights into its interactions with the ArsA ATPase | 分子名称: | Arsenical resistance operon trans-acting repressor arsD, GLYCEROL | 著者 | Ye, J, Ajees, A.A, Yang, J, Rosen, B.P. | 登録日 | 2010-05-05 | 公開日 | 2010-05-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The 1.4 A crystal structure of the ArsD arsenic metallochaperone provides insights into its interaction with the ArsA ATPase. Biochemistry, 49, 2010
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2FPD
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2FPE
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![BU of 2fpe by Molmil](/molmil-images/mine/2fpe) | Conserved dimerization of the ib1 src-homology 3 domain | 分子名称: | C-jun-amino-terminal kinase interacting protein 1, HEXAETHYLENE GLYCOL, SULFATE ION, ... | 著者 | Guenat, S, Dar, I, Bonny, C, Kastrup, J.S, Gajhede, M, Kristensen, O. | 登録日 | 2006-01-16 | 公開日 | 2006-02-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A unique set of SH3-SH3 interactions controls IB1 homodimerization Embo J., 25, 2006
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8OIT
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![BU of 8oit by Molmil](/molmil-images/mine/8oit) | 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | 分子名称: | 16S rRNA, 39S ribosomal protein L1, mitochondrial, ... | 著者 | Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. | 登録日 | 2023-03-23 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
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4P0B
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![BU of 4p0b by Molmil](/molmil-images/mine/4p0b) | Crystal structure of HOIP PUB domain in complex with OTULIN PIM | 分子名称: | E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin | 著者 | Akutsu, M, Schaeffer, V, Olma, M.H, Gomes, L.C, Kawasaki, M, Dikic, I. | 登録日 | 2014-02-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7005 Å) | 主引用文献 | Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling. Mol.Cell, 54, 2014
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6OJR
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![BU of 6ojr by Molmil](/molmil-images/mine/6ojr) | Crystal structure of Sphingomonas paucimobilis TMY1009 apo-LsdA | 分子名称: | GLYCEROL, Lignostilbene-alpha,beta-dioxygenase isozyme I, MAGNESIUM ION | 著者 | Kuatsjah, E, Verstraete, M.M, Kobylarz, M.J, Liu, A.K.N, Murphy, M.E.P, Eltis, L.D. | 登録日 | 2019-04-12 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. J.Biol.Chem., 294, 2019
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7AA2
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![BU of 7aa2 by Molmil](/molmil-images/mine/7aa2) | Chaetomium thermophilum FAD-dependent oxidoreductase in complex with ABTS | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-ETHYL-2-[(2Z)-2-(3-ETHYL-6-SULFO-1,3-BENZOTHIAZOL-2(3H)-YLIDENE)HYDRAZINO]-6-SULFO-3H-1,3-BENZOTHIAZOL-1-IUM, ... | 著者 | Svecova, L, Skalova, T, Kolenko, P, Koval, T, Oestergaard, L.H, Dohnalek, J. | 登録日 | 2020-09-03 | 公開日 | 2021-05-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum. Acta Crystallogr D Struct Biol, 77, 2021
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1OSH
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![BU of 1osh by Molmil](/molmil-images/mine/1osh) | A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR | 分子名称: | Bile acid receptor, METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE | 著者 | Downes, M, Verdecia, M.A, Roecker, A.J, Hughes, R, Hogenesch, J.B, Kast-Woelbern, H.R, Bowman, M.E, Ferrer, J.-L, Anisfeld, A.M, Edwards, P.A, Rosenfeld, J.M, Alvarez, J.G.A, Noel, J.P, Nicolaou, K.C, Evans, R.M. | 登録日 | 2003-03-19 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR Mol.Cell, 11, 2003
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6P5W
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![BU of 6p5w by Molmil](/molmil-images/mine/6p5w) | Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide | 分子名称: | 3-methyl-N-[(4S,5S)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide, Lysozyme,DCN1-like protein 1 chimera | 著者 | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | 登録日 | 2019-05-31 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019
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6P5V
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![BU of 6p5v by Molmil](/molmil-images/mine/6p5v) | Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme,DCN1-like protein 1 fusion, N-[(4S,5S)-1-[(1S)-cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide | 著者 | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | 登録日 | 2019-05-31 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | 主引用文献 | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019
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8QSJ
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![BU of 8qsj by Molmil](/molmil-images/mine/8qsj) | Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7 | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Ritter, C, Nguyen, T.G, Kummer, E. | 登録日 | 2023-10-10 | 公開日 | 2023-12-13 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome. Nat Commun, 14, 2023
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3JCT
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![BU of 3jct by Molmil](/molmil-images/mine/3jct) | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | 分子名称: | 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | 著者 | Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N. | 登録日 | 2016-03-09 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes Nature, 534, 2016
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7P71
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![BU of 7p71 by Molmil](/molmil-images/mine/7p71) | The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6 | 分子名称: | CALCIUM ION, CITRIC ACID, GLYCEROL, ... | 著者 | Gogl, G, Cousido-Siah, A, Trave, G. | 登録日 | 2021-07-19 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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2I2R
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![BU of 2i2r by Molmil](/molmil-images/mine/2i2r) | Crystal structure of the KChIP1/Kv4.3 T1 complex | 分子名称: | CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ... | 著者 | Findeisen, F, Pioletti, M, Minor Jr, D.L. | 登録日 | 2006-08-16 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer Nat.Struct.Mol.Biol., 13, 2006
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1M7J
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![BU of 1m7j by Molmil](/molmil-images/mine/1m7j) | Crystal structure of D-aminoacylase defines a novel subset of amidohydrolases | 分子名称: | ACETATE ION, D-aminoacylase, ZINC ION | 著者 | Liaw, S.-H, Chen, S.-J, Ko, T.-P, Hsu, C.-S, Wang, A.H.-J, Tsai, Y.-C. | 登録日 | 2002-07-22 | 公開日 | 2003-02-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of D-Aminoacylase from Alcaligenes faecalis DA1. A NOVEL SUBSET OF AMIDOHYDROLASES AND INSIGHTS INTO THE ENZYME MECHANISM. J.Biol.Chem., 278, 2003
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3DFV
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![BU of 3dfv by Molmil](/molmil-images/mine/3dfv) | Adjacent GATA DNA binding | 分子名称: | DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Bates, D.L, Kim, G.K, Guo, L, Chen, L. | 登録日 | 2008-06-12 | 公開日 | 2008-07-29 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA. J.Mol.Biol., 381, 2008
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2LEH
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![BU of 2leh by Molmil](/molmil-images/mine/2leh) | Solution structure of the core SMN-Gemin2 complex | 分子名称: | Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 | 著者 | Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. | 登録日 | 2011-06-15 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the core SMN-Gemin2 complex. Biochem.J., 445, 2012
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2LB3
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![BU of 2lb3 by Molmil](/molmil-images/mine/2lb3) | Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide | 分子名称: | Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | 登録日 | 2011-03-22 | 公開日 | 2011-07-06 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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8YFK
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![BU of 8yfk by Molmil](/molmil-images/mine/8yfk) | Crystal structure of FIP200 claw/TNIP1_FIR_pS123 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, RB1-inducible coiled-coil protein 1, ... | 著者 | Lv, M.Q, Wu, S.M. | 登録日 | 2024-02-24 | 公開日 | 2024-08-14 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for TNIP1 binding to FIP200 during mitophagy. J.Biol.Chem., 300, 2024
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5DIQ
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![BU of 5diq by Molmil](/molmil-images/mine/5diq) | Crystal structure of human FPPS in complex with salicylic acid derivative 3a | 分子名称: | 2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... | 著者 | Rondeau, J.M, Bourgier, E, Lehmann, S. | 登録日 | 2015-09-01 | 公開日 | 2015-09-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015
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8YFM
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8YFN
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5DJP
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