4P0B

Crystal structure of HOIP PUB domain in complex with OTULIN PIM

Summary for 4P0B

• Entry DOI: 10.2210/pdb4p0b/pdb
• Descriptor: E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin (3 entities in total)
• Functional Keywords: hoip, pub domain, otulin, pim, ligase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : Q96EP0 Q96BN8
• Total number of polymer chains: 4
• Total formula weight: 44001.24

Authors

Akutsu, M.,Schaeffer, V.,Olma, M.H.,Gomes, L.C.,Kawasaki, M.,Dikic, I. (deposition date: 2014-02-20, release date: 2014-05-07, Last modification date: 2023-12-27)

• Primary citation: Schaeffer, V.,Akutsu, M.,Olma, M.H.,Gomes, L.C.,Kawasaki, M.,Dikic, I.; Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling.; Mol.Cell, 54:349-361, 2014; PubMed: 24726327; DOI: 10.1016/j.molcel.2014.03.016

Experimental method

X-RAY DIFFRACTION (2.7005 Å)