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6ZE6
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FAD-dependent oxidoreductase from Chaetomium thermophilum in complex with fragment 4-nitrocatechol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-NITROCATECHOL, ...
著者Svecova, L, Skalova, T, Kolenko, P, Koval, T, Oestergaard, L.H, Dohnalek, J.
登録日2020-06-16
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum.
Acta Crystallogr D Struct Biol, 77, 2021
6ZE3
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FAD-dependent oxidoreductase from Chaetomium thermophilum in complex with fragment (4-methoxycarbonylphenyl)methylazanium
分子名称: (4-methoxycarbonylphenyl)methylazanium, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Svecova, L, Skalova, T, Kolenko, P, Koval, T, Oestergaard, L.H, Dohnalek, J.
登録日2020-06-16
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum.
Acta Crystallogr D Struct Biol, 77, 2021
6ZE2
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FAD-dependent oxidoreductase from Chaetomium thermophilum
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, ...
著者Svecova, L, Skalova, T, Kolenko, P, Koval, T, Oestergaard, L.H, Dohnalek, J.
登録日2020-06-16
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum.
Acta Crystallogr D Struct Biol, 77, 2021
6ZE4
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FAD-dependent oxidoreductase from Chaetomium thermophilum in complex with fragment 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl)butanamide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl)butanamide, ...
著者Svecova, L, Skalova, T, Kolenko, P, Koval, T, Oestergaard, L.H, Dohnalek, J.
登録日2020-06-16
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum.
Acta Crystallogr D Struct Biol, 77, 2021
7RR5
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BU of 7rr5 by Molmil
Structure of ribosomal complex bound with Rbg1/Tma46
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
著者Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H.
登録日2021-08-09
公開日2021-11-10
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Cell Rep, 37, 2021
7QGS
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Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid)
分子名称: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone acetyltransferase, ZINC ION
著者Hegedus, Z, Wilson, A.J, Edwards, T.A.
登録日2021-12-10
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Understanding p300-transcription factor interactions using sequence variation and hybridization.
Rsc Chem Biol, 3, 2022
7P2E
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BU of 7p2e by Molmil
Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin
分子名称: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
著者Itoh, Y, Khawaja, A, Singh, V, Rorbach, J, Amunts, A.
登録日2021-07-05
公開日2022-07-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules.
Elife, 11, 2022
5L1P
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BU of 5l1p by Molmil
X-ray Structure of Cytochrome P450 PntM with Pentalenolactone
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone
著者Duan, L, Jogl, G, Cane, D.E.
登録日2016-07-29
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism.
J.Am.Chem.Soc., 138, 2016
2Q5A
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human Pin1 bound to L-PEPTIDE
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE, Five residue peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Noel, J.P, Zhang, Y.
登録日2007-05-31
公開日2007-06-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
2FIC
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BU of 2fic by Molmil
The crystal structure of the BAR domain from human Bin1/Amphiphysin II and its implications for molecular recognition
分子名称: Myc box-dependent-interacting protein 1, XENON
著者Casal, E, Federici, L, Zhang, W, Fernandez-Recio, J, Priego, E.M, Miguel, R.N, Duhadaway, J.B, Prendergast, G.C, Luisi, B.F, Laue, E.D.
登録日2005-12-29
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition
Biochemistry, 45, 2006
2MDI
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BU of 2mdi by Molmil
Solution structure of the PP2WW mutant (KPP2WW) of HYPB
分子名称: Histone-lysine N-methyltransferase SETD2
著者Gao, Y.G, Hu, H.Y.
登録日2013-09-10
公開日2014-09-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin.
Structure, 22, 2014
2LXL
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Lip5(mit)2
分子名称: Vacuolar protein sorting-associated protein VTA1 homolog
著者Skalicky, J.J, Sundquist, W.I.
登録日2012-08-29
公開日2012-11-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport.
J.Biol.Chem., 287, 2012
5OOL
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BU of 5ool by Molmil
Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V.
登録日2017-08-08
公開日2017-09-13
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
5L8V
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BU of 5l8v by Molmil
Apo-structure of humanised RadA-mutant humRadA4
分子名称: DNA repair and recombination protein RadA, PHOSPHATE ION
著者Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日2016-06-08
公開日2016-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5LB4
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BU of 5lb4 by Molmil
Apo-structure of humanised RadA-mutant humRadA14
分子名称: DNA repair and recombination protein RadA
著者Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日2016-06-15
公開日2016-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5LBI
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BU of 5lbi by Molmil
Apo-structure of humanised RadA-mutant humRadA3
分子名称: CALCIUM ION, DNA repair and recombination protein RadA
著者Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日2016-06-16
公開日2016-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5KVS
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BU of 5kvs by Molmil
Substrate Analog and NADP+ bound structure of Irp3, a Thiazolinyl Imine Reductase from Yersinia enterocolitica
分子名称: (4~{R})-2-[2-(2-hydroxyphenyl)-1,3-thiazol-4-yl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid, 1,2-ETHANEDIOL, FORMIC ACID, ...
著者Meneely, K.M, Lamb, A.L.
登録日2016-07-15
公開日2016-09-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis.
Biochemistry, 55, 2016
5KIO
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BU of 5kio by Molmil
PSEUDO T4 LYSOZYME MUTANT - Y18PHE-I
分子名称: 2-HYDROXYETHYL DISULFIDE, Endolysin
著者Scholfield, M.R.
登録日2016-06-16
公開日2017-04-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structure-Energy Relationships of Halogen Bonds in Proteins.
Biochemistry, 56, 2017
4FR3
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BU of 4fr3 by Molmil
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H
分子名称: (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, MAGNESIUM ION, ...
著者Ottmann, C, Anders, C, Schumacher, B.
登録日2012-06-26
公開日2013-05-08
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface.
Chem.Biol., 20, 2013
8SS0
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Human sterol 14 alpha-demethylase (CYP51) in complex with the reaction intermediate 14 alpha-aldehyde dihydrolanosterol
分子名称: 3beta-hydroxy-10alpha,13alpha-lanosta-8,24-dien-30-al, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE
著者Hargrove, T.Y, Wawrzak, Z, Guengerich, F.P, Lepesheva, G.I.
登録日2023-05-08
公開日2024-01-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Oxygen-18 Labeling Reveals a Mixed Fe-O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14 alpha-Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
5KVQ
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BU of 5kvq by Molmil
NADP+ bound structure of Irp3, a Thiazolinyl Imine Reductase from Yersinia enterocolitica
分子名称: 1,2-ETHANEDIOL, Irp3 protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Meneely, K.M, Lamb, A.L.
登録日2016-07-15
公開日2016-09-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis.
Biochemistry, 55, 2016
5LB2
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BU of 5lb2 by Molmil
Apo-structure of humanised RadA-mutant humRadA2
分子名称: DNA repair and recombination protein RadA
著者Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日2016-06-15
公開日2016-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
8SR6
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BU of 8sr6 by Molmil
Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (3-17)peptide
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Eukaryotic huntingtin interacting protein B, ...
著者Xu, C, Chung, I.Y.W, Cygler, M.
登録日2023-05-05
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Histone methyltransferase activity of the secreted Legionella pneumophila SET-domain effector RomA/LegAS4 depends on its ankyrin domain
To Be Published
6J8Y
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BU of 6j8y by Molmil
Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex
分子名称: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ...
著者Hara, K, Iida, N, Sakurai, H, Hashimoto, H.
登録日2019-01-21
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp.
J.Biol.Chem., 295, 2020
5IWW
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Crystal structure of RNA editing factor of designer PLS-type PPR/9R protein in complex with MORF9/RIP9
分子名称: Multiple organellar RNA editing factor 9, chloroplastic, PLS9-PPR
著者Yan, J, Zhang, Q, Guan, Z, Zou, T, Yin, P.
登録日2016-03-23
公開日2017-03-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing
Nat Plants, 3, 2017

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件を2024-09-04に公開中

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