PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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3ZDQ	STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM) 分子名称: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL, CARDIOLIPIN, ... 著者 Pike, A.C.W, Shintre, C.A, Krojer, T, von Delft, F, Vollmar, M, Mukhopadhyay, S, Burgess-Brown, N, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Carpenter, E.P. 登録日 2012-11-30 公開日 2013-01-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States Proc.Natl.Acad.Sci.USA, 110, 2013
3ZPO	Crystal structure of JmjC domain of human histone demethylase UTY with bound GSK J1 分子名称: 1,2-ETHANEDIOL, 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, FE (II) ION, ... 著者 Vollmar, M, Gileadi, C, Shrestha, L, Goubin, S, Johansson, C, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Human Uty(Kdm6C) is a Male-Specific Nepislon-Methyl Lysyl Demethylase. J.Biol.Chem., 289, 2014
5T0L	Crystal structure of Toxoplasma gondii TS-DHFR complexed with NADPH, dUMP, PDDF and 5-(4-(3,4-dichlorophenyl)piperazin-1-yl)pyrimidine-2,4-diamine (TRC-15) 分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-[4-(3,4-dichlorophenyl)piperazin-1-yl]pyrimidine-2,4-diamine, ... 著者 Thomas, S.B, Chen, Z, Lu, H, Li, Y. 登録日 2016-08-16 公開日 2016-09-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design. ACS Med Chem Lett, 7, 2016
3ZMC	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound substrate molecule Geranyl pyrophosphate. 分子名称: DIMETHYL SULFOXIDE, GERANYL DIPHOSPHATE, GERANYLTRANSTRANSFERASE, ... 著者 Schmidberger, J.W, Schnell, R, Schneider, G. 登録日 2013-02-07 公開日 2014-02-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa Acta Crystallogr.,Sect.D, 71, 2015
4N6T	Adhiron: a stable and versatile peptide display scaffold - full length adhiron 分子名称: Adhiron 著者 Mcpherson, M, Tomlinson, D, Owen, R.L, Nettleship, J.E, Owens, R.J. 登録日 2013-10-14 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. Protein Eng.Des.Sel., 27, 2014
3ZO4	The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-(4-PHENYL-1,9-DIAZASPIRO[5.5]UNDECAN-9-YL)-9H-PURINE, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... 著者 Allen, C.E, Chow, C.L, Caldwell, J.J, Westwood, I.M, van Montfort, R.L, Collins, I. 登録日 2013-02-20 公開日 2013-03-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases. Bioorg. Med. Chem., 21, 2013
4MZK	Crystal Structure of MTIP from Plasmodium falciparum in complex with pGly[807,811], a stapled myoA tail peptide 分子名称: Myosin A tail domain interacting protein, pGly[807,811], a stapled myoA tail peptide 著者 Douse, C.H, Garnett, J.A, Maas, S.J, Cota, E, Tate, E.W. 登録日 2013-09-30 公開日 2013-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction. Acs Chem.Biol., 8, 2014
3ZPL	Crystal structure of Sco3205, a MarR family transcriptional regulator from Streptomyces coelicolor, in complex with DNA 分子名称: 5'-D(*AP*AP*AP*GP*AP*TP*TP*GP*AP*GP*AP*TP*CP*TP *CP*AP*AP*TP*CP*TP*TP*DT)-3', PHOSPHATE ION, PUTATIVE MARR-FAMILY TRANSCRIPTIONAL REPRESSOR 著者 Stevenson, C.E.M, Assaad, A, Lawson, D.M. 登録日 2013-02-28 公開日 2013-07-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Investigation of DNA Sequence Recognition by a Streptomycete Marr Family Transcriptional Regulator Through Surface Plasmon Resonance and X-Ray Crystallography. Nucleic Acids Res., 41, 2013
3ZL9	Crystal structure of the nucleocapsid protein from Schmallenberg virus 分子名称: NUCLEOCAPSID PROTEIN 著者 Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. 登録日 2013-01-29 公開日 2013-05-01 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization. Nucleic Acids Res., 41, 2013
3ZLA	Crystal structure of the nucleocapsid protein from Bunyamwera virus bound to RNA 分子名称: NUCLEOPROTEIN, RNA 著者 Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. 登録日 2013-01-29 公開日 2013-05-01 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization. Nucleic Acids Res., 41, 2013
5VMP	Crystal Structure of Human KDM4 with Small Molecule Inhibitor QC5714 分子名称: 3-({[(1R)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}amino)pyridine-4-carboxylic acid, Lysine-specific demethylase 4A, NICKEL (II) ION, ... 著者 Hosfield, D.J. 登録日 2017-04-28 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models. ACS Med Chem Lett, 8, 2017
5VOM	Benzopiperazine BET bromodomain inhibitor in complex with BD1 of Brd4 分子名称: 3-[(2S)-1-acetyl-4-(furan-2-carbonyl)-2-methyl-1,2,3,4-tetrahydroquinoxalin-6-yl]-N-methylbenzamide, Bromodomain-containing protein 4 著者 Toms, A.V, Herbertz, T. 登録日 2017-05-03 公開日 2017-08-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains. ACS Med Chem Lett, 8, 2017
4BKP	Crystal structure of human GDP-L-fucose synthase with bound NADP 分子名称: 1,2-ETHANEDIOL, CITRATE ANION, GDP-L-FUCOSE SYNTHASE, ... 著者 Vollmar, M, Shafqat, N, Rojkova, A, Krojer, T, Bradley, A, Raynor, J.W, Kavanagh, K, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U, Yue, W.W. 登録日 2013-04-29 公開日 2013-06-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp To be Published
4BC3	Crystal structure of human D-xylulokinase 分子名称: 1,2-ETHANEDIOL, XYLULOSE KINASE 著者 Bunker, R.D, Loomes, K.M, Baker, E.N. 登録日 2012-10-01 公開日 2012-11-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
4BIK	Structure of a disulfide locked mutant of Intermedilysin with human CD59 分子名称: CD59 GLYCOPROTEIN, INTERMEDILYSIN 著者 Johnson, S, Brooks, N.J, Smith, R.A.G, Lea, S.M, Bubeck, D. 登録日 2013-04-10 公開日 2013-05-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.494 Å) 主引用文献 Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59 Cell Rep., 3, 2013
4BK3	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Y105F mutant 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
4BKN	Human Dihydropyrimidinase-related protein 3 (DPYSL3) 分子名称: DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 著者 Mathea, S, Elkins, J.M, Alegre-Abarrategui, J, Shrestha, L, Burgess-Brown, N, Puranik, S, Coutandin, D, Bradley, A, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A, Knapp, S. 登録日 2013-04-26 公開日 2013-05-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Dpysl3 To be Published
4BJS	Crystal structure of the Rif1 C-terminal domain (Rif1-CTD) from Saccharomyces cerevisiae 分子名称: TELOMERE LENGTH REGULATOR PROTEIN RIF1 著者 Bunker, R.D, Shi, T, Gut, H, Scrima, A, Thoma, N.H. 登録日 2013-04-19 公開日 2013-06-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions Cell(Cambridge,Mass.), 153, 2013
4BIY	Crystal structure of CpxAHDC (monoclinic form 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4AW6	Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 (FACE1) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CAAX PRENYL PROTEASE 1 HOMOLOG, ZINC ION 著者 Pike, A.C.W, Dong, Y.Y, Quigley, A, Dong, L, Cooper, C.D.O, Chaikuad, A, Goubin, S, Shrestha, L, Li, Q, Mukhopadhyay, S, Yang, J, Xia, X, Shintre, C.A, Barr, A.J, Berridge, G, Chalk, R, Bray, J.E, von Delft, F, Bullock, A, Bountra, C, Arrowsmith, C.H, Edwards, A, Burgess-Brown, N, Carpenter, E.P. 登録日 2012-05-31 公開日 2012-07-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 The Structural Basis of Zmpste24-Dependent Laminopathies. Science, 339, 2013
4BIW	Crystal structure of CpxAHDC (hexagonal form) 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SENSOR PROTEIN CPXA, ... 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4BIU	Crystal structure of CpxAHDC (orthorhombic form 1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4BMB	Crystal structure of the N terminal domain of human Galectin 8 分子名称: GALECTIN-8, GLYCEROL, SODIUM ION, ... 著者 Buzamet, E, Ruiz, F.M, Menendez, M, Romero, A, Gabius, H.J, Solis, D. 登録日 2013-05-07 公開日 2014-03-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.351 Å) 主引用文献 Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells. FEBS J., 281, 2014
4C55	Crystal structure of serum-derived human IgG4 Fc 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, IG GAMMA-4 CHAIN C REGION, ... 著者 Davies, A.M, Rispens, T, Ooijevaar-deHeer, P, Gould, H.J, Jefferis, R, Aalberse, R.C, Sutton, B.J. 登録日 2013-09-10 公開日 2013-11-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Determinants of Unique Properties of Human Igg4-Fc J.Mol.Biol., 426, 2014
4CCC	STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH 4NBDG: ENZYME-SUBSTRATE COMPLEX 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrophenyl beta-D-galactopyranoside, ... 著者 Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E. 登録日 2013-10-21 公開日 2013-12-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease Proc.Natl.Acad.Sci.USA, 110, 2013

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