3ZPO
Crystal structure of JmjC domain of human histone demethylase UTY with bound GSK J1
Summary for 3ZPO
Entry DOI | 10.2210/pdb3zpo/pdb |
Related | 3ZLI |
Descriptor | HISTONE DEMETHYLASE UTY, 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, ZINC ION, ... (6 entities in total) |
Functional Keywords | hydrolase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus : O14607 |
Total number of polymer chains | 2 |
Total formula weight | 112089.37 |
Authors | Vollmar, M.,Gileadi, C.,Shrestha, L.,Goubin, S.,Johansson, C.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U. (deposition date: 2013-02-28, release date: 2013-05-29, Last modification date: 2023-12-20) |
Primary citation | Walport, L.J.,Hopkinson, R.J.,Vollmar, M.,Madden, S.K.,Gileadi, C.,Oppermann, U.,Schofield, C.J.,Johansson, C. Human Uty(Kdm6C) is a Male-Specific Nepislon-Methyl Lysyl Demethylase. J.Biol.Chem., 289:18302-, 2014 Cited by PubMed: 24798337DOI: 10.1074/JBC.M114.555052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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