4C55

Crystal structure of serum-derived human IgG4 Fc

Summary for 4C55

• Entry DOI: 10.2210/pdb4c55/pdb
• Related: 4C54
• Descriptor: IG GAMMA-4 CHAIN C REGION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: immune system, igg, antibody, immunoglobulin, igg1
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P01861
• Total number of polymer chains: 2
• Total formula weight: 52966.99

Authors

Davies, A.M.,Rispens, T.,Ooijevaar-deHeer, P.,Gould, H.J.,Jefferis, R.,Aalberse, R.C.,Sutton, B.J. (deposition date: 2013-09-10, release date: 2013-11-13, Last modification date: 2023-12-20)

• Primary citation: Davies, A.M.,Rispens, T.,Ooijevaar-Deheer, P.,Gould, H.J.,Jefferis, R.,Aalberse, R.C.,Sutton, B.J.; Structural Determinants of Unique Properties of Human Igg4-Fc; J.Mol.Biol., 426:630-, 2014; PubMed: 24211234; DOI: 10.1016/J.JMB.2013.10.039

Experimental method

X-RAY DIFFRACTION (2.35 Å)