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3I4N
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8-oxoguanine containing RNA polymerase II elongation complex E
分子名称: DNA (5'-D(*AP*G*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*(8OG)P*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Damsma, G.E, Cramer, P.
登録日2009-07-02
公開日2009-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Molecular basis of transcriptional mutagenesis at 8-oxoguanine
J.Biol.Chem., 284, 2009
3I4M
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8-oxoguanine containing RNA polymerase II elongation complex D
分子名称: DNA (5'-D(*AP*G*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*(8OG)P*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Damsma, G.E, Cramer, P.
登録日2009-07-02
公開日2009-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Molecular basis of transcriptional mutagenesis at 8-oxoguanine
J.Biol.Chem., 284, 2009
8TVS
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BU of 8tvs by Molmil
Cryo-EM structure of backtracked Pol II in complex with Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVQ
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BU of 8tvq by Molmil
Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVX
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BU of 8tvx by Molmil
Cryo-EM structure of CPD-stalled Pol II (Conformation 2)
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TUG
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BU of 8tug by Molmil
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state)
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-16
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVW
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BU of 8tvw by Molmil
Cryo-EM structure of CPD-stalled Pol II (conformation 1)
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVV
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BU of 8tvv by Molmil
Cryo-EM structure of backtracked Pol II
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVP
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BU of 8tvp by Molmil
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state)
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
5U5Q
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BU of 5u5q by Molmil
12 Subunit RNA Polymerase II at Room Temperature collected using SFX
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A.
登録日2016-12-07
公開日2017-03-29
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep, 7, 2017
4FLA
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BU of 4fla by Molmil
Crystal structure of human RPRD1B, carboxy-terminal domain
分子名称: Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION
著者Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC)
登録日2012-06-14
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
1HQM
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BU of 1hqm by Molmil
CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K.
登録日2000-12-18
公開日2001-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
7EU1
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BU of 7eu1 by Molmil
The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme
分子名称: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerases II and IV subunit 5A, DNA-directed RNA polymerases II, ...
著者Fang, C.L, Wu, X.X, Huang, K, Zhang, Y.
登録日2021-05-15
公開日2021-12-29
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
7EU0
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BU of 7eu0 by Molmil
The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex
分子名称: DNA (33-MER), DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase IV subunit 1, ...
著者Fang, C.L, Wu, X.X, Huang, K, Zhang, Y.
登録日2021-05-15
公開日2021-12-29
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
6NPW
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BU of 6npw by Molmil
SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
分子名称: PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ...
著者Irani, S, Zhang, Y.
登録日2019-01-18
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.
J.Biol.Chem., 294, 2019
5LVF
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BU of 5lvf by Molmil
Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide
分子名称: PRO-SER-TYR-SER-PRO-PTH-SER-PRO-SER-TYR-SER-PRO-THR-SER-PRO-SER, Regulator of Ty1 transposition protein 103
著者Jasnovidova, O, Kubicek, K, Krejcikova, M, Stefl, R.
登録日2016-09-14
公開日2017-05-10
最終更新日2019-10-30
実験手法SOLUTION NMR
主引用文献Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p.
EMBO Rep., 18, 2017
7KKF
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BU of 7kkf by Molmil
Crystal Structure of S. cerevisiae Ess1
分子名称: Peptidyl-prolyl cis-trans isomerase ESS1
著者Namitz, K.E.W, Alicea-Velazquez, N.L, Cosgrove, M.S, Hanes, S.D.
登録日2020-10-27
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism.
Commun Biol, 4, 2021
8DH0
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BU of 8dh0 by Molmil
T7 RNA polymerase elongation complex with unnatural base dDs
分子名称: GLYCEROL, Non-template strand DNA, RNA, ...
著者Oh, J, Wang, D.
登録日2022-06-24
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase.
Nat Commun, 14, 2023
7UM1
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BU of 7um1 by Molmil
Structure of bacteriophage AR9 non-virion RNAP polymerase holoenzyme determined by cryo-EM
分子名称: DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ...
著者Leiman, P.G, Fraser, A, Sokolova, M.L.
登録日2022-04-05
公開日2022-07-06
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase.
Nat Commun, 13, 2022
2O5I
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BU of 2o5i by Molmil
Crystal structure of the T. thermophilus RNA polymerase elongation complex
分子名称: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ...
著者Vassylyev, D.G, Tahirov, T.H, Vassylyeva, M.N.
登録日2006-12-06
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for transcription elongation by bacterial RNA polymerase.
Nature, 448, 2007
6XKB
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BU of 6xkb by Molmil
Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD
分子名称: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION
著者Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2020-06-26
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
Febs Lett., 596, 2022
8A8F
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BU of 8a8f by Molmil
Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
分子名称: MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ...
著者Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A.
登録日2022-06-22
公開日2023-11-29
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription.
Mol.Cell, 83, 2023
5OHO
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BU of 5oho by Molmil
Crystal structure of the KOWx-KOW4 domain of human DSIF
分子名称: CHLORIDE ION, GLYCEROL, Transcription elongation factor SPT5
著者Bernecky, C, Plitzko, J.M, Cramer, P.
登録日2017-07-17
公開日2017-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp.
Nat. Struct. Mol. Biol., 24, 2017
4YGX
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BU of 4ygx by Molmil
Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide
分子名称: LD40846p, Symplekin, cis peptidomimetic CTD phospho-Ser5 peptide
著者Mayfield, J.E, Zhang, Y.
登録日2015-02-26
公開日2015-09-16
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
7NVX
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TFIIH in a post-translocated state (with ADP-BeF3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ...
著者Aibara, S, Schilbach, S, Cramer, P.
登録日2021-03-16
公開日2021-05-05
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021

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