1UVL
 
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5nt RNA. Conformation B | | 分子名称: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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1UVM
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5NT RNA conformation A | | 分子名称: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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1UVK
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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1ZYR
 | | Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... | | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | | 登録日 | 2005-06-10 | | 公開日 | 2005-09-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
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3HKZ
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4QIW
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6IZX
 | | The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678 | | 分子名称: | 2-oxo-2H-1,3-benzoxathiol-5-yl acetate, COBALT (II) ION, Genome polyprotein, ... | | 著者 | Shimizu, H, Sekine, S. | | 登録日 | 2018-12-20 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase.
Plos Negl Trop Dis, 13, 2019
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6IZY
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7Q0J
 | | RNA polymerase elongation complex in more-swiveled conformation | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-15 | | 公開日 | 2022-03-23 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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3LU0
 | | Molecular model of Escherichia coli core RNA polymerase | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Darst, S.A. | | 登録日 | 2010-02-16 | | 公開日 | 2010-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (11.2 Å) | | 主引用文献 | Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
Plos Biol., 8, 2010
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4H3H
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5MDU
 | | Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe. | | 分子名称: | CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ... | | 著者 | Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J. | | 登録日 | 2016-11-13 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | | 主引用文献 | The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
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4QJV
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4NC7
 | | N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions | | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | | 著者 | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | | 登録日 | 2013-10-24 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
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4NC8
 | | N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions | | 分子名称: | DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | | 著者 | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | | 登録日 | 2013-10-24 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
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6IRZ
 | | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA | | 分子名称: | 1,2-ETHANEDIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, PDX1 C-terminal-inhibiting factor 1, ... | | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2018-11-15 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
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4B02
 | | The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase | | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | 著者 | Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. | | 登録日 | 2012-06-27 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase.
Virology, 432, 2012
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2JLF
 | | STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE | | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | 著者 | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | 登録日 | 2008-09-08 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
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4PZ7
 | | PCE1 guanylyltransferase | | 分子名称: | GLYCEROL, SULFATE ION, mRNA-capping enzyme subunit alpha | | 著者 | Doamekpor, S.K, Lima, C.D. | | 登録日 | 2014-03-28 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.109 Å) | | 主引用文献 | How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
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4PZ8
 | | PCE1 guanylyltransferase bound to SPT5 CTD | | 分子名称: | SULFATE ION, Transcription elongation factor spt5, mRNA-capping enzyme subunit alpha | | 著者 | Doamekpor, S.K, Lima, C.D. | | 登録日 | 2014-03-28 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
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2JLG
 | | STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE | | 分子名称: | 5'-D(*DT DT DT DC DCP)-3', GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | 著者 | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | 登録日 | 2008-09-09 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
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3N6L
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1IW7
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4RY5
 | | C-terminal mutant (W550N) of HCV/J4 RNA polymerase | | 分子名称: | HCV J4 RNA polymerase (NS5B), MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE | | 著者 | Jaeger, J, Cherry, A, Dennis, C. | | 登録日 | 2014-12-13 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
J.Virol., 89, 2015
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4FLB
 | | CID of human RPRD2 | | 分子名称: | PRASEODYMIUM ION, Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, ... | | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-14 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
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