6IZY
The RNA-dependent RNA polymerase domain of dengue 2 NS5
Summary for 6IZY
| Entry DOI | 10.2210/pdb6izy/pdb |
| Related | 6IZX |
| Descriptor | Genome polyprotein, COBALT (II) ION, ZINC ION, ... (4 entities in total) |
| Functional Keywords | dengue, ns5, rna-dependent rna polymerase, viral protein |
| Biological source | Dengue virus 2 |
| Total number of polymer chains | 1 |
| Total formula weight | 79928.19 |
| Authors | Shimizu, H.,Sekine, S. (deposition date: 2018-12-20, release date: 2019-12-25, Last modification date: 2023-11-22) |
| Primary citation | Shimizu, H.,Saito, A.,Mikuni, J.,Nakayama, E.E.,Koyama, H.,Honma, T.,Shirouzu, M.,Sekine, S.I.,Shioda, T. Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase. Plos Negl Trop Dis, 13:e0007894-e0007894, 2019 Cited by PubMed: 31738758DOI: 10.1371/journal.pntd.0007894 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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