PDB: 489 件ウェブページステータス検索Chemie searchBIRD

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6CM3	BG505 SOSIP in complex with sCD4, 17b, 8ANC195 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wang, H, Bjorkman, P.J. 登録日 2018-03-02 公開日 2018-10-17 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host Microbe, 24, 2018
7T0O	cryoEM reconstruction of the HIV gp140 in complex with the extracellular domains of CD4 and the adnectin domain of Combinectin. The gp140 and CD4 coordinates from entry 6EDU were rigid body fitted to the EM map along withe the crystal structure of CD4+adnectin 分子名称: Adnectin, BG505 SOSIP.664 gp140, T-cell surface glycoprotein CD4 著者 Concha, N.O, William, S.P, Wenzel, D.L. 登録日 2021-11-30 公開日 2022-01-12 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment. J.Mol.Biol., 434, 2021
4JM2	Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab 分子名称: 17b Heavy chain, 17b Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kong, L, Wilson, I.A. 登録日 2013-03-13 公開日 2013-05-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat.Struct.Mol.Biol., 20, 2013
6OPN	CD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6X5C	Asymmetric model of CD4-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2020-05-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (4.04 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6X5B	Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2020-05-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
5U1F	Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145 分子名称: BG505 DS-SOSIP gp120, BG505 SOSIP gp41, PGT145 heavy chain, ... 著者 Acharya, P, Kwong, P.D, Potter, C.S, Carragher, B. 登録日 2016-11-28 公開日 2017-02-22 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer. Nat. Struct. Mol. Biol., 24, 2017
5VN3	Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Pallesen, J, Ward, A.B. 登録日 2017-04-28 公開日 2017-07-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature, 547, 2017
5THR	Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex 分子名称: 17b Fab VH domain, 17b Fab VL domain, 8ANC195 G52K5 VH domain, ... 著者 Wang, H, Bjorkman, P.J. 登録日 2016-09-30 公開日 2016-11-16 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (8.9 Å) 主引用文献 Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop. Proc.Natl.Acad.Sci.USA, 113, 2016
8FYI	Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Fan, C, Dam, K.A, Bjorkman, P.J. 登録日 2023-01-26 公開日 2023-10-18 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Intermediate conformations of CD4-bound HIV-1 Env heterotrimers. Nature, 623, 2023
8FYJ	Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Fan, C, Dam, K.A, Bjorkman, P.J. 登録日 2023-01-26 公開日 2023-10-18 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Intermediate conformations of CD4-bound HIV-1 Env heterotrimers. Nature, 623, 2023
6MET	Structural basis of coreceptor recognition by HIV-1 envelope spike 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Shaik, M.M, Chen, B. 登録日 2018-09-07 公開日 2018-12-12 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural basis of coreceptor recognition by HIV-1 envelope spike. Nature, 565, 2018
6MEO	Structural basis of coreceptor recognition by HIV-1 envelope spike 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Shaik, M.M, Chen, B. 登録日 2018-09-06 公開日 2018-12-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of coreceptor recognition by HIV-1 envelope spike. Nature, 565, 2018
6OPO	Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020

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