6X5B

Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52

Summary for 6X5B

Entry DOI	10.2210/pdb6x5b/pdb
EMDB information	22048
Descriptor	Envelope glycoprotein gp120, Envelope glycoprotein gp41, 17b Fab light chain, ... (9 entities in total)
Functional Keywords	hiv-1, env, cd4, receptor-bound state, small molecule, viral protein, viral protein-immune system complex
Biological source	Human immunodeficiency virus 1 (HIV-1) More
Total number of polymer chains	15
Total formula weight	452528.23
Authors	Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2020-05-25, release date: 2020-10-21, Last modification date: 2020-12-09)
Primary citation	Ozorowski, G.,Torres, J.L.,Santos-Martins, D.,Forli, S.,Ward, A.B. A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33:108428-108428, 2020 Cited by PubMed: 33238117 DOI: 10.1016/j.celrep.2020.108428 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation