5G18
| Direct Observation of Active-site Protonation States in a Class A beta lactamase with a monobactam substrate | 分子名称: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, BETA-LACTAMASE CTX-M-97, SULFATE ION | 著者 | Vandavasi, V.G, Weiss, K.L, Parks, J.M, Cooper, J.B, Ginell, S.L, Coates, L. | 登録日 | 2016-03-23 | 公開日 | 2016-11-09 | 最終更新日 | 2019-10-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate. Antimicrob. Agents Chemother., 61, 2017
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5FAP
| CTX-M-15 in complex with FPI-1602 | 分子名称: | Beta-lactamase, [[(3~{R},6~{S})-6-[(azetidin-3-ylcarbonylamino)carbamoyl]-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate | 著者 | King, A.M, King, D.T, French, S, Brouillette, E, Asli, A, Alexander, A.N, Vuckovic, M, Maiti, S.N, Parr, T.R, Brown, E.D, Malouin, F, Strynadka, N.C.J, Wright, G.D. | 登録日 | 2015-12-11 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. Acs Chem.Biol., 11, 2016
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5FAO
| CTX-M-15 in complex with FPI-1465 | 分子名称: | Beta-lactamase, [[(3~{R},6~{S})-1-methanoyl-6-[[(3~{S})-pyrrolidin-3-yl]oxycarbamoyl]piperidin-3-yl]amino] hydrogen sulfate | 著者 | King, A.M, King, D.T, French, S, Brouillette, E, Asli, A, Alexander, A.N, Vuckovic, M, Maiti, S.N, Parr, T.R, Brown, E.D, Malouin, F, Strynadka, N.C.J, Wright, G.D. | 登録日 | 2015-12-11 | 公開日 | 2016-02-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. Acs Chem.Biol., 11, 2016
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5FA7
| CTX-M-15 in complex with FPI-1523 | 分子名称: | Beta-lactamase, [[(3~{R},6~{S})-6-(acetamidocarbamoyl)-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate | 著者 | King, A.M, King, D.T, French, S, Brouillette, E, Asli, A, Alexander, A.N, Vuckovic, M, Maiti, S.N, Parr, T.R, Brown, E.D, Malouin, F, Strynadka, N.C.J, Wright, G.D. | 登録日 | 2015-12-11 | 公開日 | 2016-01-20 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. Acs Chem.Biol., 11, 2016
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5F83
| Imipenem complex of the GES-5 C69G mutant | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase | 著者 | Smith, C.A, Vakulenko, S.B. | 登録日 | 2015-12-09 | 公開日 | 2016-09-07 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Role of the Conserved Disulfide Bridge in Class A Carbapenemases. J.Biol.Chem., 291, 2016
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5F82
| Apo GES-5 C69G mutant | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase | 著者 | Smith, C.A, Vakulenko, S.B. | 登録日 | 2015-12-08 | 公開日 | 2016-09-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | Role of the Conserved Disulfide Bridge in Class A Carbapenemases. J.Biol.Chem., 291, 2016
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5F1G
| Crystal structure of AmpC BER adenylylated in the cytoplasm | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Beta-lactamase, ... | 著者 | An, Y.J, Kim, M.K, Na, J.H, Cha, S.S. | 登録日 | 2015-11-30 | 公開日 | 2016-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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5F1F
| Crystal structure of CMY-10 adenylylated by acetyl-AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Beta-lactamase, CADMIUM ION | 著者 | An, Y.J, Kim, M.K, Na, J.H, Cha, S.S. | 登録日 | 2015-11-30 | 公開日 | 2016-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.548 Å) | 主引用文献 | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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5EVL
| Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Chromobacterium violaceum | 分子名称: | Beta-lactamase, CHLORIDE ION, GLYCEROL, ... | 著者 | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-11-19 | 公開日 | 2015-12-02 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Chromobacterium violaceum To Be Published
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5EVI
| Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Pseudomonas syringae | 分子名称: | 1,2-ETHANEDIOL, Beta-Lactamase/D-Alanine Carboxypeptidase, SULFATE ION | 著者 | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-11-19 | 公開日 | 2016-01-13 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Pseudomonas syringae To Be Published
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5EUA
| Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam | 分子名称: | (2R)-2-[(1R)-1-{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}-1-methoxy-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3 -oxazine-4-carboxylic acid, Beta-lactamase, SODIUM ION | 著者 | Pozzi, C, De Luca, F, Benvenuti, M, Docquier, J.D, Mangani, S. | 登録日 | 2015-11-18 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem. Antimicrob.Agents Chemother., 60, 2016
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5EPH
| Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Imipenem | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Pozzi, C, Benvenuti, M, De Luca, F, Docquier, J.D, Mangani, S. | 登録日 | 2015-11-11 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem. Antimicrob.Agents Chemother., 60, 2016
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5EOO
| Crystal structure of extended-spectrum beta-lactamase BEL-1 (monoclinic form) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Pozzi, C, De Luca, F, Benvenuti, M, Docquier, J.D, Mangani, S. | 登録日 | 2015-11-10 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem. Antimicrob.Agents Chemother., 60, 2016
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5EOE
| Crystal structure of extended-spectrum beta-lactamase BEL-1 (orthorhombic form) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, Beta-lactamase, ... | 著者 | Pozzi, C, De Luca, F, Benvenuti, M, Docquier, J.D, Mangani, S. | 登録日 | 2015-11-10 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem. Antimicrob.Agents Chemother., 60, 2016
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5EEC
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5EE8
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5E43
| Crystal Structure of Beta-lactamase Sros_5706 from Streptosporangium roseum | 分子名称: | ACETATE ION, Beta-lactamase, NITRATE ION | 著者 | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-10-05 | 公開日 | 2015-10-14 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.7095 Å) | 主引用文献 | Crystal Structure of Beta-lactamase Sros_5706 from Streptosporangium roseum To Be Published
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5E2H
| Crystal Structure of D-alanine Carboxypeptidase AmpC from Mycobacterium smegmatis | 分子名称: | Beta-lactamase, CHLORIDE ION, GLYCEROL | 著者 | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-10-01 | 公開日 | 2015-10-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of D-alanine Carboxypeptidase AmpC from Mycobacterium smegmatis To Be Published
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5E2G
| Crystal Structure of D-alanine Carboxypeptidase AmpC from Burkholderia cenocepacia | 分子名称: | ACETIC ACID, Beta-lactamase, THIOCYANATE ION | 著者 | Kim, Y, Joachimiak, G, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-10-01 | 公開日 | 2015-10-14 | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | 主引用文献 | Crystal Structure of D-alanine Carboxypeptidase AmpC from Burkholderia cenocepacia To Be Published
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5E2E
| Crystal Structure of Beta-lactamase Precursor BlaA from Yersinia enterocolitica | 分子名称: | Beta-lactamase | 著者 | Kim, Y, Joachimiak, G, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-10-01 | 公開日 | 2015-10-28 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of Beta-lactamase Precursor BlaA from Yersinia enterocolitica To Be Published
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5CHU
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with sulfate | 分子名称: | ACETATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-10 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with sulfate To Be Published
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5CHM
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with ceftazidime BATSI (LP06) | 分子名称: | ACETATE ION, Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-10 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors. Biomolecules, 10, 2020
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5CHJ
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with cephalothin BATSI (SM23) | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, ACETATE ION, Beta-lactamase, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-10 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.358 Å) | 主引用文献 | Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors. Biomolecules, 10, 2020
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5CGX
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F complexed with cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, SODIUM ION, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
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5CGW
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
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