5EUA
Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam
Replaces: 4MXHSummary for 5EUA
Entry DOI | 10.2210/pdb5eua/pdb |
Related | 5EOE 5EOO 5EPH |
Descriptor | Beta-lactamase, (2R)-2-[(1R)-1-{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}-1-methoxy-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3 -oxazine-4-carboxylic acid, SODIUM ION, ... (4 entities in total) |
Functional Keywords | hydrolase-antibiotic complex, extended-spectrum beta-lactamase, pseudomonas aeruginosa, oxacephem antibiotic, hydrolase/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 58702.05 |
Authors | Pozzi, C.,De Luca, F.,Benvenuti, M.,Docquier, J.D.,Mangani, S. (deposition date: 2015-11-18, release date: 2016-09-21, Last modification date: 2024-01-10) |
Primary citation | Pozzi, C.,De Luca, F.,Benvenuti, M.,Poirel, L.,Nordmann, P.,Rossolini, G.M.,Mangani, S.,Docquier, J.D. Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem. Antimicrob.Agents Chemother., 60:7189-7199, 2016 Cited by PubMed: 27671060DOI: 10.1128/AAC.00936-16 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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