5FAP

CTX-M-15 in complex with FPI-1602

Summary for 5FAP

Entry DOI	10.2210/pdb5fap/pdb
Related	5FA7 5FAO 5FAQ 5FAS 5FAT
Descriptor	Beta-lactamase, [[(3~{R},6~{S})-6-[(azetidin-3-ylcarbonylamino)carbamoyl]-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate (3 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	57008.38
Authors	King, A.M.,King, D.T.,French, S.,Brouillette, E.,Asli, A.,Alexander, A.N.,Vuckovic, M.,Maiti, S.N.,Parr, T.R.,Brown, E.D.,Malouin, F.,Strynadka, N.C.J.,Wright, G.D. (deposition date: 2015-12-11, release date: 2016-01-20, Last modification date: 2023-09-27)
Primary citation	King, A.M.,King, D.T.,French, S.,Brouillette, E.,Asli, A.,Alexander, J.A.,Vuckovic, M.,Maiti, S.N.,Parr, T.R.,Brown, E.D.,Malouin, F.,Strynadka, N.C.,Wright, G.D. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. Acs Chem.Biol., 11:864-868, 2016 Cited by PubMed: 26731698 DOI: 10.1021/acschembio.5b00944 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation