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2F87
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Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus
分子名称: SRP RNA
著者Okada, K, Takahashi, M, Sakamoto, T, Nakamura, K, Kanai, A, Kawai, G
登録日2005-12-02
公開日2006-08-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus
Nucleosides Nucleotides Nucleic Acids, 25, 2006
2D17
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Solution RNA structure of stem-bulge-stem region of the HIV-1 dimerization initiation site
分子名称: 5'-R(*CP*GP*GP*CP*AP*AP*GP*AP*GP*GP*CP*GP*AP*CP*CP*C)-3', 5'-R(*GP*GP*GP*UP*CP*GP*GP*CP*UP*UP*GP*CP*UP*G)-3'
著者Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G.
登録日2005-08-15
公開日2005-11-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
2D18
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Solution RNA structure of loop region of the HIV-1 dimerization initiation site in the extended-duplex dimer
分子名称: 5'-R(*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*GP*GP*C)-3'
著者Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G.
登録日2005-08-15
公開日2005-11-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
2CYX
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Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)
分子名称: Ubiquitin-conjugating enzyme E2 G2
著者Yoshikawa, S, Arai, R, Murayama, K, Imai, Y, Takahashi, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-08
公開日2006-04-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)
Acta Crystallogr.,Sect.F, 62, 2006
2D1B
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Solution RNA structure model of the HIV-1 dimerization initiation site in the kissing-loop dimer
分子名称: RNA
著者Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G.
登録日2005-08-15
公開日2005-11-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
2D1A
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Solution RNA structure model of the HIV-1 dimerization initiation site in the extended-duplex dimer
分子名称: RNA
著者Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G.
登録日2005-08-15
公開日2005-11-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
2CYC
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Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Pyrococcus horikoshii
分子名称: TYROSINE, tyrosyl-tRNA synthetase
著者Kuratani, M, Sakai, H, Takahashi, M, Yanagisawa, T, Kobayashi, T, Sakamoto, K, Terada, T, Shirouzu, M, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-06
公開日2005-11-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
J.Mol.Biol., 355, 2006
2CYA
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Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix
分子名称: SULFATE ION, Tyrosyl-tRNA synthetase
著者Kuratani, M, Sakai, H, Takahashi, M, Yanagisawa, T, Kobayashi, T, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Kuroishi, C, Kuramitsu, S, Terada, T, Bessho, Y, Shirouzu, M, Sekine, S.I, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-06
公開日2005-11-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
J.Mol.Biol., 355, 2005
7VPC
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Neryl diphosphate synthase from Solanum lycopersicum
分子名称: 1,2-ETHANEDIOL, D-MALATE, Neryl-diphosphate synthase 1
著者Imaizumi, R, Misawa, S, Takeshita, K, Sakai, N, Yamamoto, M, Kataoka, K, Nakayama, T, Takahashi, S, Yamashita, S.
登録日2021-10-15
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure-based engineering of a short-chain cis-prenyltransferase to biosynthesize nonnatural all-cis-polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain-length determination.
Febs J., 289, 2022
7WAB
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Crystal structure of the prolyl endoprotease, PEP, from Aspergillus niger
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPASS (Complex proteins associated with Set1p) component shg1 family protein, ...
著者Miyazono, K, Kubota, K, Takahashi, K, Tanokura, M.
登録日2021-12-14
公開日2022-01-12
最終更新日2022-02-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure and substrate recognition mechanism of the prolyl endoprotease PEP from Aspergillus niger.
Biochem.Biophys.Res.Commun., 591, 2022
6J5L
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Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e
分子名称: High affinity nerve growth factor receptor, N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide
著者Kensuke, A, Kazutaka, I.
登録日2019-01-11
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain.
Bioorg.Med.Chem.Lett., 29, 2019
7WMC
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Crystal structure of macrocyclic peptide 1 bound to human Nicotinamide N-methyltransferase
分子名称: Nicotinamide N-methyltransferase, Peptide1
著者Yoshida, S, Uehara, S, Kondo, N, Takahashi, Y, Yamamoto, S, Kameda, A, Kawagoe, S, Inoue, N, Yamada, M, Yoshimura, N, Tachibana, Y.
登録日2022-01-14
公開日2022-08-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides.
J.Med.Chem., 65, 2022
7WMT
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Crystal structure of small molecule 13 bound to human Nicotinamide N-methyltransferase
分子名称: Nicotinamide N-methyltransferase, [(2~{R},4~{S})-4-[2-(aminomethyl)imidazol-1-yl]-2-[1-[(4-chlorophenyl)methyl]-5-methyl-indol-2-yl]pyrrolidin-1-yl]-(1~{H}-pyrrolo[2,3-b]pyridin-5-yl)methanone
著者Yoshida, S, Uehara, S, Kondo, N, Takahashi, Y, Yamamoto, S, Kameda, A, Kawagoe, S, Inoue, N, Yamada, M, Yoshimura, N, Tachibana, Y.
登録日2022-01-17
公開日2022-08-31
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides.
J.Med.Chem., 65, 2022
7VUS
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Crystal structure of AlleyCat9 with 5-nitro-benzotriazole
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1H-benzotriazole, AlleyCat, ...
著者Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
登録日2021-11-04
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
7VUR
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Crystal structure of AlleyCat9 with calcium but no inhibitor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AlleyCat, CALCIUM ION
著者Margheritis, E, Takahashi, K, Korendovych, I.V, Tame, J.R.H.
登録日2021-11-04
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
7VUU
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Crystal structure of AlleyCat10 with inhibitor
分子名称: 5-nitro-1H-benzotriazole, AlleyCat, CALCIUM ION
著者Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
登録日2021-11-04
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
7VUT
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Crystal structure of AlleyCat10
分子名称: AlleyCat10, CALCIUM ION
著者Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
登録日2021-11-04
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
7VY3
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STRUCTURE OF PHOTOSYNTHETIC LH1-RC SUPER-COMPLEX OF RHODOBACTER SPHAEROIDES LACKING PROTEIN-U
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ...
著者Tani, K, Kanno, R, Kawamura, S, Kikuchi, R, Nagashima, K.V.P, Hall, M, Takahashi, A, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y.
登録日2021-11-13
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Asymmetric structure of the native Rhodobacter sphaeroides dimeric LH1-RC complex.
Nat Commun, 13, 2022
7VY2
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STRUCTURE OF PHOTOSYNTHETIC LH1-RC SUPER-COMPLEX OF RHODOBACTER SPHAEROIDES DIMER
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ...
著者Tani, K, Kanno, R, Kawamura, S, Kikuchi, R, Nagashima, K.V.P, Hall, M, Takahashi, A, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y.
登録日2021-11-13
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Asymmetric structure of the native Rhodobacter sphaeroides dimeric LH1-RC complex.
Nat Commun, 13, 2022
7Y8P
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Crystal structure of 4'-selenoRNA duplex
分子名称: COBALT HEXAMMINE(III), RNA (5'-R(*GP*GP*AP*(IKS)P*(ILK)P*(IKS)P*GP*AP*GP*UP*CP*C)-3')
著者Kondo, J, Minakawa, N, Ohta, M, Takahashi, H, Tarashima, N.
登録日2022-06-24
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis and properties of fully-modified 4'-selenoRNA, an endonuclease-resistant RNA analog.
Bioorg.Med.Chem., 76, 2022
7WCI
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The 0.85 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with two molecules of pelargonic acid
分子名称: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ...
著者Sugiyama, S, Kakinouchi, K, Takahashi, J, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2021-12-20
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献The 0.85 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with two molecules of pelargonic acid
To Be Published
6KBI
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Crystal structure of ErbB3 N418Q mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-3
著者Kato, K, Yao, M.
登録日2019-06-25
公開日2020-07-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of ErbB3 N418Q mutant
To Be Published
7X9U
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Type-II KH motif of human mitochondrial RbfA
分子名称: Putative ribosome-binding factor A, mitochondrial
著者Kuwasako, K, Suzuki, S, Furue, M, Takizawa, M, Takahashi, M, Tsuda, K, Nagata, T, Watanabe, S, Tanaka, A, Kobayashi, N, Kigawa, T, Guntert, P, Shirouzu, M, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2022-03-16
公開日2023-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1 H, 13 C, and 15 N resonance assignments and solution structures of the KH domain of human ribosome binding factor A, mtRbfA, involved in mitochondrial ribosome biogenesis.
Biomol.Nmr Assign., 16, 2022
7YH6
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Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-8 Fab heavy chain, NIV-8 Fab light chain, ...
著者Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y.
登録日2022-07-12
公開日2023-07-19
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.
Nat Commun, 14, 2023
7YH7
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SARS-CoV-2 spike in complex with neutralizing antibody NIV-8 (state 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-8 Fab heavy chain, ...
著者Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y.
登録日2022-07-13
公開日2023-07-19
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.
Nat Commun, 14, 2023

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