7WMC
Crystal structure of macrocyclic peptide 1 bound to human Nicotinamide N-methyltransferase
Summary for 7WMC
Entry DOI | 10.2210/pdb7wmc/pdb |
Descriptor | Nicotinamide N-methyltransferase, Peptide1 (3 entities in total) |
Functional Keywords | nicotinamide n-methyltransferase, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 61416.57 |
Authors | Yoshida, S.,Uehara, S.,Kondo, N.,Takahashi, Y.,Yamamoto, S.,Kameda, A.,Kawagoe, S.,Inoue, N.,Yamada, M.,Yoshimura, N.,Tachibana, Y. (deposition date: 2022-01-14, release date: 2022-08-31, Last modification date: 2023-11-15) |
Primary citation | Yoshida, S.,Uehara, S.,Kondo, N.,Takahashi, Y.,Yamamoto, S.,Kameda, A.,Kawagoe, S.,Inoue, N.,Yamada, M.,Yoshimura, N.,Tachibana, Y. Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides. J.Med.Chem., 65:10655-10673, 2022 Cited by PubMed: 35904556DOI: 10.1021/acs.jmedchem.2c00919 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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