7YH6

Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-8

Summary for 7YH6

• Entry DOI: 10.2210/pdb7yh6/pdb
• EMDB information: 33820
• Descriptor: NIV-8 Fab light chain, NIV-8 Fab heavy chain, Spike protein S1, ... (4 entities in total)
• Functional Keywords: complex, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 47445.67

Authors

Moriyama, S.,Anraku, Y.,Muranishi, S.,Adachi, Y.,Kuroda, D.,Higuchi, Y.,Kotaki, R.,Tonouchi, K.,Yumoto, K.,Suzuki, T.,Kita, S.,Fukuhara, H.,Kuroda, Y.,Yamamoto, T.,Onodera, T.,Fukushi, S.,Maeda, K.,Nakamura-Uchiyama, F.,Hashiguchi, T.,Hoshino, A.,Maenaka, K.,Takahashi, Y. (deposition date: 2022-07-12, release date: 2023-07-19, Last modification date: 2023-10-25)

• Primary citation: Moriyama, S.,Anraku, Y.,Taminishi, S.,Adachi, Y.,Kuroda, D.,Kita, S.,Higuchi, Y.,Kirita, Y.,Kotaki, R.,Tonouchi, K.,Yumoto, K.,Suzuki, T.,Someya, T.,Fukuhara, H.,Kuroda, Y.,Yamamoto, T.,Onodera, T.,Fukushi, S.,Maeda, K.,Nakamura-Uchiyama, F.,Hashiguchi, T.,Hoshino, A.,Maenaka, K.,Takahashi, Y.; Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.; Nat Commun, 14:4198-4198, 2023; PubMed: 37452031; DOI: 10.1038/s41467-023-39890-8

Experimental method

ELECTRON MICROSCOPY (3.4 Å)