PDB: 102 件ウェブページステータス検索Chemie searchBIRD

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2ZPY	Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide 分子名称: CD44 antigen, Radixin 著者 Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T. 登録日 2008-07-31 公開日 2008-08-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for CD44 recognition by ERM proteins J.Biol.Chem., 283, 2008
3BIN	Structure of the DAL-1 and TSLC1 (372-383) complex 分子名称: Band 4.1-like protein 3, Cell adhesion molecule 1 著者 Busam, R.D, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Berglund, H, Persson, C, Hallberg, B.M. 登録日 2007-11-30 公開日 2008-01-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B) J.Biol.Chem., 286, 2011
4RMA	Crystal structure of the FERM domain of human ezrin 分子名称: Ezrin, SULFATE ION 著者 Phang, J.M, Harrop, S.J, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-21 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
2I1J	Moesin from Spodoptera frugiperda at 2.1 angstroms resolution 分子名称: CHLORIDE ION, GLYCEROL, Moesin, ... 著者 Li, Q, Nance, M.R, Tesmer, J.J.G. 登録日 2006-08-14 公開日 2006-12-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain. J.Mol.Biol., 365, 2007
4RM8	Crystal structure of human ezrin in space group P21 分子名称: Ezrin 著者 Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-20 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
8CIT	The FERM domain of human moesin mutant L281R 分子名称: Moesin 著者 Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.536 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIU	The FERM domain of human moesin mutant H288A 分子名称: Moesin 著者 Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIR	The FERM domain of human moesin with a bound peptide identified by phage display 分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIS	The FERM domain of human moesin with two bound peptides identified by phage display 分子名称: 1,2-ETHANEDIOL, ACETATE ION, C3P, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
4ZRK	Merlin-FERM and Lats1 complex 分子名称: Merlin, Serine/threonine-protein kinase LATS1 著者 Lin, Z, Li, Y, Wei, Z, Zhang, M. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.316 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
1GG3	CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN 分子名称: ERYTHROID MEMBRANE PROTEIN 4.1R 著者 Han, B.G. 登録日 2000-07-11 公開日 2001-01-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization. Nat.Struct.Biol., 7, 2000
4ZRI	Crystal structure of Merlin-FERM and Lats2 分子名称: Merlin, Serine/threonine-protein kinase LATS2 著者 Li, F, Zhou, H, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
1GC6	CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE 分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN 著者 Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. 登録日 2000-07-21 公開日 2000-09-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
4ZRJ	Structure of Merlin-FERM and CTD 分子名称: GLYCEROL, Merlin 著者 Lin, Z, Li, F, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
1GC7	CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN 分子名称: RADIXIN 著者 Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. 登録日 2000-07-21 公開日 2000-09-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
6D2Q	Crystal structure of the FERM domain of zebrafish FARP1 分子名称: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 著者 Kuo, Y.C, Zhang, X. 登録日 2018-04-13 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
6D21	Crystal structure of the FERM domain of zebrafish FARP2 分子名称: FERM, RhoGEF and pleckstrin domain protein 2 著者 Kuo, Y.C, Zhang, X. 登録日 2018-04-12 公開日 2018-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
6CDS	Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ... 著者 Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T. 登録日 2018-02-09 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2. Nat Commun, 9, 2018
1H4R	Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. 分子名称: MERLIN, SULFATE ION 著者 Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. 登録日 2001-05-14 公開日 2002-01-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product. Acta Crystallogr.,Sect.D, 58, 2002
4YL8	Crystal structure of the Crumbs/Moesin complex 分子名称: GLYCEROL, IODIDE ION, Moesin, ... 著者 Wei, Z, Li, Y, Zhang, M. 登録日 2015-03-05 公開日 2015-04-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin J.Biol.Chem., 290, 2015
6D2K	Crystal structure of the FERM domain of mouse FARP2 分子名称: FERM, ARHGEF and pleckstrin domain-containing protein 2 著者 He, X, Zhang, X. 登録日 2018-04-13 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
2D11	Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide 分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin 著者 Terawaki, S, Maesaki, R, Hakoshima, T. 登録日 2005-08-11 公開日 2006-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structural basis for NHERF recognition by ERM proteins Structure, 14, 2006
2D2Q	Crystal structure of the dimerized radixin FERM domain 分子名称: Radixin 著者 Kitano, K, Yusa, F, Hakoshima, T. 登録日 2005-09-15 公開日 2006-04-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304 ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2EMS	Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43 分子名称: Leukosialin, Radixin 著者 Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. 登録日 2007-03-28 公開日 2008-04-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins J.Mol.Biol., 381, 2008
2EMT	Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1 分子名称: P-selectin glycoprotein ligand 1, Radixin 著者 Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. 登録日 2007-03-28 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of PSGL-1 binding to ERM proteins Genes Cells, 12, 2007

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