8CIR
The FERM domain of human moesin with a bound peptide identified by phage display
Summary for 8CIR
Entry DOI | 10.2210/pdb8cir/pdb |
Descriptor | Moesin, C3P, BROMIDE ION, ... (6 entities in total) |
Functional Keywords | pip, ferm domain, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 88122.24 |
Authors | Bradshaw, W.J.,Katis, V.L.,Leisner, T.M.,Fairhead, M.,Bountra, C.,von Delft, F.,Pearce, K.H.,Brennan, P.E. (deposition date: 2023-02-10, release date: 2023-03-01, Last modification date: 2023-11-29) |
Primary citation | Du, Y.,Bradshaw, W.J.,Leisner, T.M.,Annor-Gyamfi, J.K.,Qian, K.,Bashore, F.M.,Sikdar, A.,Nwogbo, F.O.,Ivanov, A.A.,Frye, S.V.,Gileadi, O.,Brennan, P.E.,Levey, A.I.,Axtman, A.D.,Pearce, K.H.,Fu, H.,Katis, V.L. Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299:105382-105382, 2023 Cited by PubMed: 37866628DOI: 10.1016/j.jbc.2023.105382 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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