PDB: 57 件ウェブページステータス検索Chemie searchBIRD

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3MHZ	1.7A structure of 2-fluorohistidine labeled Protective Antigen 分子名称: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL 著者 Lovell, S, Battaile, K.P, Wimalasena, D.S, Janowiak, B.E, Miyagi, M, Sun, J, Hajduch, J, Pooput, C, Kirk, K.L, Bann, J.G. 登録日 2010-04-09 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation. Biochemistry, 49, 2010
3KWV	Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers 分子名称: CALCIUM ION, Lethal factor, Protective antigen PA-63 著者 Feld, G.K, Kintzer, A.F, Krantz, B.A. 登録日 2009-12-01 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers. Nat.Struct.Mol.Biol., 17, 2010
3TEW	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution 分子名称: 2-METHOXYETHANOL, CALCIUM ION, Protective antigen 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEX	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution 分子名称: CALCIUM ION, Protective antigen 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEZ	Crystal Structure of Anthrax Protective Antigen Mutant S337C N664C and dithiolacetone modified to 1.8-A resolution 分子名称: 2-METHOXYETHANOL, ACETONE, CALCIUM ION, ... 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2012-05-23 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEY	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution 分子名称: CALCIUM ION, Protective antigen 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2012-05-23 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
8DCM	Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab 分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ... 著者 Goldsmith, J.A, McLellan, J.S. 登録日 2022-06-16 公開日 2023-04-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin. J.Bacteriol., 205, 2023
8EKM	Clostridioides difficile binary toxin translocase CDTb double mutant - D623A D734A 分子名称: ADP-ribosyltransferase binding component, CALCIUM ION 著者 Abeyawardhane, D.L, Pozharski, E. 登録日 2022-09-21 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
8EKK	Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 2 分子名称: ADP-ribosyltransferase binding component, CALCIUM ION 著者 Abeyawardhane, D.L, Pozharski, E. 登録日 2022-09-21 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
8EKL	Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 1 分子名称: ADP-ribosyltransferase binding component, CALCIUM ION 著者 Abeyawardhane, D.L, Pozharski, E. 登録日 2022-09-21 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
3Q8C	Crystal structure of Protective Antigen W346F (pH 5.5) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8A	Crystal structure of WT Protective Antigen (pH 5.5) 分子名称: CALCIUM ION, Protective antigen 著者 Rajapaksha, M, Lovell, S, Janowiak, B.E, Andra, K.K, Battaile, K.P, Bann, J.G. 登録日 2011-01-06 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.129 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8F	Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8) 分子名称: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8B	Crystal structure of WT Protective Antigen (pH 9.0) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8E	Crystal structure of Protective Antigen W346F (pH 8.5) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
6O2O	CDTb Double Heptamer Short Form Modeled from Cryo-EM Map Reconstructed using C1 Symmetry 分子名称: ADP-ribosyltransferase binding component 著者 Lacy, D.B, Sheedlo, M.J, Anderson, D.M. 登録日 2019-02-24 公開日 2019-10-30 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.53 Å) 主引用文献 Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKU	CDTb Double Heptamer Long Form Mask 3 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry 分子名称: ADP-ribosyltransferase binding component 著者 Lacy, D.B, Sheedlo, M.J, Anderson, D.M. 登録日 2019-04-15 公開日 2019-10-30 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKS	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry 分子名称: ADP-ribosyltransferase binding component 著者 Lacy, D.B, Sheedlo, M.J, Anderson, D.M. 登録日 2019-04-15 公開日 2019-10-30 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKT	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry 分子名称: ADP-ribosyltransferase binding component 著者 Lacy, D.B, Sheedlo, M.J, Anderson, D.M. 登録日 2019-04-15 公開日 2019-10-30 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKR	CDTb Pre-Insertion form Modeled from Cryo-EM Map Reconstructed using C7 Symmetry 分子名称: ADP-ribosyltransferase binding component 著者 Lacy, D.B, Sheedlo, M.J, Anderson, D.M. 登録日 2019-04-15 公開日 2019-10-30 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6PSN	Anthrax toxin protective antigen channels bound to lethal factor 分子名称: CALCIUM ION, Lethal factor, Protective antigen 著者 Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. 登録日 2019-07-12 公開日 2020-03-04 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
6UWI	Crystal structure of the Clostridium difficile translocase CDTb 分子名称: ADP-ribosyltransferase binding component, CALCIUM ION 著者 Pozharski, E. 登録日 2019-11-05 公開日 2020-01-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6UZB	Anthrax toxin protective antigen channels bound to edema factor 分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen 著者 Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. 登録日 2019-11-14 公開日 2020-03-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
6UWT	Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation 分子名称: ADP-ribosyltransferase binding component, CALCIUM ION 著者 Xu, X, Pozharski, E, des Georges, A. 登録日 2019-11-05 公開日 2020-01-22 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6V1S	Structure of the Clostridioides difficile transferase toxin 分子名称: ADP-ribosylating binary toxin enzymatic subunit CdtA, ADP-ribosyltransferase binding component, CALCIUM ION 著者 Sheedlo, M.J, Anderson, D.M, Thomas, A.K, Lacy, D.B. 登録日 2019-11-21 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme. Proc.Natl.Acad.Sci.USA, 117, 2020

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