2DRD
| Crystal structure of a multidrug transporter reveal a functionally rotating mechanism | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, ACRB | 著者 | Murakami, S, Nakashima, R, Yamashita, E, Matsumoto, T. | 登録日 | 2006-06-08 | 公開日 | 2006-08-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443, 2006
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2DR6
| Crystal structure of a multidrug transporter reveal a functionally rotating mechanism | 分子名称: | ACRB, DOXORUBICIN | 著者 | Murakami, S, Nakashima, R, Yamashita, E, Matsumoto, T. | 登録日 | 2006-06-08 | 公開日 | 2006-08-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443, 2006
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2DHH
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2W1B
| The structure of the efflux pump AcrB in complex with bile acid | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B | 著者 | Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. | 登録日 | 2008-10-17 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | 主引用文献 | The Structure of the Efflux Pump Acrb in Complex with Bile Acid. Mol.Membr.Biol., 25, 2008
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4K7Q
| Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution | 分子名称: | Acriflavine resistance protein B, N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide | 著者 | Hung, L.W, Kim, H.B, Murakami, S, Gupta, G, Kim, C.Y, Terwilliger, T.C. | 登録日 | 2013-04-17 | 公開日 | 2013-07-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of AcrB complexed with linezolid at 3.5 Angstrom resolution. J.Struct.Funct.Genom., 14, 2013
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3KSS
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4U8V
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Pos, K.M. | 登録日 | 2014-08-04 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB. Elife, 3, 2014
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4U95
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Pos, K.M. | 登録日 | 2014-08-05 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB eLife, 3, 2014
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3K07
| Crystal structure of CusA | 分子名称: | Cation efflux system protein cusA | 著者 | Su, C.-C. | 登録日 | 2009-09-24 | 公開日 | 2010-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.521 Å) | 主引用文献 | Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature, 467, 2010
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4U96
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7RR7
| Multidrug efflux pump subunit AcrB | 分子名称: | DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE | 著者 | Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Multidrug efflux pump subunit AcrB To Be Published
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7RR8
| Multidrug efflux pump subunit AcrB | 分子名称: | DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE | 著者 | Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Multidrug efflux pump subunit AcrB To Be Published
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7RR6
| Multidrug efflux pump subunit AcrB | 分子名称: | DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE | 著者 | Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Multidrug efflux pump subunit AcrB To Be Published
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9BFM
| Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor | 分子名称: | (2S)-1-(3,4-dichlorophenoxy)-3-(4-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}piperidin-1-yl)propan-2-ol, Multidrug efflux pump subunit AcrB | 著者 | Su, C.C. | 登録日 | 2024-04-18 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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9BFH
| Cryo-EM co-structure of AcrB with the CU032 efflux pump inhibitor | 分子名称: | (2S)-1-[(3R)-3-aminopyrrolidin-1-yl]-3-(3,4-dichlorophenoxy)propan-2-ol, Multidrug efflux pump subunit AcrB | 著者 | Su, C.C. | 登録日 | 2024-04-17 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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9BFT
| Cryo-EM co-structure of AcrB with CU244 | 分子名称: | (2S)-1-{[(1R,5R)-3-azabicyclo[3.1.0]hexan-6-yl]amino}-3-(3,5-dichlorophenoxy)propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB | 著者 | Su, C.C. | 登録日 | 2024-04-18 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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9BFN
| Cryo-EM co-structure of AcrB with the CU232 efflux pump inhibitor | 分子名称: | (2R)-1-(4-aminopiperidin-1-yl)-3-[3-(trifluoromethyl)phenoxy]propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB | 著者 | Su, C.C. | 登録日 | 2024-04-18 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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4U8Y
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Pos, K.M. | 登録日 | 2014-08-05 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB. Elife, 3, 2014
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7RY3
| Multidrug Efflux pump AdeJ with TP-6076 bound | 分子名称: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, Efflux pump membrane transporter | 著者 | Zhang, Z. | 登録日 | 2021-08-24 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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3KSO
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3AOD
| Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, RIFAMPICIN | 著者 | Nakashima, R, Sakurai, K, Yamaguchi, A. | 登録日 | 2010-09-23 | 公開日 | 2011-11-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
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3AOB
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7KF6
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7KF8
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7KF5
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