7RY3
Multidrug Efflux pump AdeJ with TP-6076 bound
Summary for 7RY3
| Entry DOI | 10.2210/pdb7ry3/pdb |
| EMDB information | 24732 |
| Descriptor | Efflux pump membrane transporter, (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (2 entities in total) |
| Functional Keywords | multidrug efflux pump, membrane protein-antibiotic complex, membrane protein/antibiotic |
| Biological source | Acinetobacter baumannii |
| Total number of polymer chains | 3 |
| Total formula weight | 344492.91 |
| Authors | Zhang, Z. (deposition date: 2021-08-24, release date: 2022-02-02, Last modification date: 2024-06-05) |
| Primary citation | Morgan, C.E.,Zhang, Z.,Bonomo, R.A.,Yu, E.W. An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13:e0373221-e0373221, 2022 Cited by PubMed: 35100868DOI: 10.1128/mbio.03732-21 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.91 Å) |
Structure validation
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