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1WF6
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The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
分子名称: Similar to S.pombe -rad4+/cut5+product (A40727)
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-26
公開日2004-11-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
TO BE PUBLISHED
2NTE
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Crystal Structure of the BARD1 BRCT Domains
分子名称: 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ...
著者Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A.
登録日2006-11-07
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
1Z56
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Co-Crystal Structure of Lif1p-Lig4p
分子名称: DNA ligase IV, Ligase interacting factor 1
著者Dore, A.S, Furnham, N, Davies, O.R, Sibanda, B.L, Chirgadze, D.Y, Jackson, S.P, Pellegrini, L, Blundell, T.L.
登録日2005-03-17
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.92 Å)
主引用文献Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.
DNA REPAIR, 5, 2006
1L0B
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BU of 1l0b by Molmil
Crystal Structure of rat Brca1 tandem-BRCT region
分子名称: BRCA1
著者Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P.
登録日2002-02-08
公開日2002-03-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
Genes Dev., 16, 2002
1JNX
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Crystal structure of the BRCT repeat region from the breast cancer associated protein, BRCA1
分子名称: BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, NICKEL (II) ION
著者Williams, R.S, Green, R, Glover, J.N.M.
登録日2001-07-26
公開日2001-09-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1.
Nat.Struct.Biol., 8, 2001
1L7B
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Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT
分子名称: DNA LIGASE
著者Sahota, G, Dixon, B.L, Huang, Y.P, Aramini, J, Monleon, D, Bhattacharya, D, Swapna, G.V.T, Yin, C, Xiao, R, Anderson, S, Tejero, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2002-03-14
公開日2003-09-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Brct Domain from Thermus Thermophilus DNA Ligase
To be Published
1Y98
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Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
著者Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2004-12-14
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
2R1Z
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Crystal Structure of the BARD1 BRCT Repeat
分子名称: BRCA1-associated RING domain protein 1, GLYCEROL
著者Lee, M.S, Edwards, R.A, Williams, R.S, Glover, M.J.N.
登録日2007-08-23
公開日2007-09-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the BARD1 BRCT Repeat
To be Published
4BMD
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Crystal structure of S.pombe Rad4 BRCT3,4
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, S-M CHECKPOINT CONTROL PROTEIN RAD4
著者Meng, Q, Rappas, M, Wardlaw, C.P, Garcia, V, Carr, A.M, Oliver, A.W, Du, L.L, Pearl, L.H.
登録日2013-05-07
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(Topbp1.).
Mol.Cell, 51, 2013
2XNH
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Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1
分子名称: DNA TOPOISOMERASE 2-BINDING PROTEIN 1, IODIDE ION
著者Rappas, M, Oliver, A.W, Pearl, L.H.
登録日2010-08-02
公開日2010-09-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1.
Nucleic Acids Res., 39, 2011
2XNK
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Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1
分子名称: DNA TOPOISOMERASE 2-BINDING PROTEIN 1, GLYCEROL
著者Rappas, M, Oliver, A.W, Pearl, L.H.
登録日2010-08-03
公開日2010-09-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1.
Nucleic Acids Res., 39, 2011
1T29
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Crystal structure of the BRCA1 BRCT repeats bound to a phosphorylated BACH1 peptide
分子名称: BACH1 phosphorylated peptide, Breast cancer type 1 susceptibility protein
著者Shiozaki, E.N, Gu, L, Yan, N, Shi, Y.
登録日2004-04-20
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling.
Mol.Cell, 14, 2004
2ING
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X-ray Structure of the BRCA1 BRCT mutant M1775K
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2006-10-07
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2K7F
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HADDOCK calculated model of the complex between the BRCT region of RFC p140 and dsDNA
分子名称: 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3', Replication factor C subunit 1
著者Kobayashi, M, Ab, E, Bonvin, A, Siegal, G.
登録日2008-08-10
公開日2009-09-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex.
J.Biol.Chem., 285, 2010
1T15
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Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase
分子名称: BRCA1 interacting protein C-terminal helicase 1, Breast cancer type 1 susceptibility protein
著者Clapperton, J.A, Manke, I.A, Lowery, D.M, Ho, T, Haire, L.F, Yaffe, M.B, Smerdon, S.J.
登録日2004-04-15
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
Nat.Struct.Mol.Biol., 11, 2004
2K6G
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Solution structure of the DNA binding BRCT domain from the large subunit of human Replication Factor C
分子名称: Replication factor C subunit 1
著者Kobayashi, M, Siegal, G, Ab, E, Bonvin, A.M.J.J.
登録日2008-07-09
公開日2009-09-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA bound BRCT domain from human Replication Factor C p140
To be Published
1T2V
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Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
分子名称: BRCTide-7PS, Breast cancer type 1 susceptibility protein
著者Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
3AL2
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Crystal Structure of TopBP1 BRCT7/8
分子名称: DNA topoisomerase 2-binding protein 1, SULFATE ION
著者Leung, C.C, Glover, J.N.
登録日2010-07-22
公開日2010-12-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3AL3
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Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex
分子名称: DNA topoisomerase 2-binding protein 1, FORMIC ACID, Peptide of Fanconi anemia group J protein
著者Leung, C.C, Glover, J.N.
登録日2010-07-22
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
1T2U
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Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
2LE0
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PARP BRCT Domain
分子名称: Poly [ADP-ribose] polymerase 1
著者Mueller, G, Loeffler, P, Cuneo, M, Derose, E, London, R.
登録日2011-06-03
公開日2011-10-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural studies of the PARP-1 BRCT domain.
Bmc Struct.Biol., 11, 2011
3JVE
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Crystal Structure of the Sixth BRCT Domain of TopBP1
分子名称: DNA topoisomerase 2-binding protein 1
著者Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
登録日2009-09-16
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
3K16
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Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-25
公開日2010-03-02
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0H
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The crystal structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with an amidated C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-24
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K15
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Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with an amidated C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-25
公開日2010-03-02
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010

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