2XNK

Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1

Summary for 2XNK

Entry DOI	10.2210/pdb2xnk/pdb
Related	1WF6 2XNH
Descriptor	DNA TOPOISOMERASE 2-BINDING PROTEIN 1, GLYCEROL (3 entities in total)
Functional Keywords	isomerase, phosphorylation, protein-protein interaction, dna repair
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: Q92547
Total number of polymer chains	4
Total formula weight	138266.86
Authors	Rappas, M.,Oliver, A.W.,Pearl, L.H. (deposition date: 2010-08-03, release date: 2010-09-01, Last modification date: 2023-12-20)
Primary citation	Rappas, M.,Oliver, A.W.,Pearl, L.H. Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1. Nucleic Acids Res., 39:313-, 2011 Cited by PubMed: 20724438 DOI: 10.1093/NAR/GKQ743 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation