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2XNK

Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
DNA TOPOISOMERASE 2-BINDING PROTEIN 1polymer29234313.54UniProt (Q92547)
Pfam (PF00533)
HOMO SAPIENS (HUMAN)DNA TOPOISOMERASE II-BINDING PROTEIN 1, DNA TOPOISOMERASE II-BETA-BINDING PROTEIN 1, TOPBP1
2E, F, G, H, I...
(A, B, C, D)
GLYCEROLnon-polymer92.111Chemie (GOL)
3P, Q, R, S
(A, B, C, D)
waterwater18.0340Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 290 (UniProt: Q92547)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight137253.8
Non-Polymers*Number of molecules11
Total formula weight1013.0
All*Total formula weight138266.9
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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