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3K16

Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus

Summary for 3K16
Entry DOI10.2210/pdb3k16/pdb
Related3K05 3K0H 3K0K 3K14
DescriptorBreast cancer type 1 susceptibility protein, phospho peptide, NICKEL (II) ION, ... (5 entities in total)
Functional Keywordsbrca1, brct domain, dna damage response, phospho peptide interactions, abraxas, isomerase, alternative initiation, cell cycle, disease mutation, dna damage, dna repair, dna-binding, fatty acid biosynthesis, ligase, lipid synthesis, metal-binding, nucleus, phosphoprotein, tumor suppressor, ubl conjugation pathway, zinc-finger
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus . Isoform 3: Cytoplasm. Isoform 5: Cytoplasm : P38398
Total number of polymer chains2
Total formula weight25273.06
Authors
Campbell, S.J.,Edwards, R.A.,Glover, J.N. (deposition date: 2009-09-25, release date: 2010-03-02, Last modification date: 2021-10-13)
Primary citationCampbell, S.J.,Edwards, R.A.,Glover, J.N.
Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18:167-176, 2010
Cited by
PubMed: 20159462
DOI: 10.1016/j.str.2009.12.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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