PDB: 294 件ウェブページステータス検索Chemie searchBIRD

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8Z0U	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-10 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal protein human Beta-catenin To Be Published
8Z5J	Beta-catenin Crystal Structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-18 公開日 2024-05-22 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67, 2024
8Z61	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-18 公開日 2024-05-08 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67, 2024
7UWI	Structure of beta-catenin in complex with FP01567, a Helicon Polypeptide 分子名称: Catenin beta-1, GLYCEROL, Helicon Polypeptide FP01567, ... 著者 Brennan, M, Agarwal, S, Thomson, T, Wahl, S, Ramirez, J, Verdine, G, McGee, J. 登録日 2022-05-03 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7UWO	Structure of beta-catenin in complex with FP05874, a Helicon Polypeptide 分子名称: Catenin beta-1, Helicon Polypeptide FP05874, N,N'-(1,4-phenylene)diacetamide 著者 Agarwal, S, Thomson, T, Wahl, S, Ramirez, J, Hriniak, B, Verdine, G, McGee, J. 登録日 2022-05-03 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
5XGC	Crystal structure of SmgGDS-558 分子名称: Rap1 GTPase-GDP dissociation stimulator 1 著者 Shimizu, H, Toma-Fukai, S, Shimizu, T. 登録日 2017-04-13 公開日 2017-06-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding J. Biol. Chem., 292, 2017
5XJG	Crystal structure of Vac8p bound to Nvj1p 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Nucleus-vacuole junction protein 1, ... 著者 Jeong, H, Park, J, Jun, Y, Lee, C. 登録日 2017-05-01 公開日 2017-06-07 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1G3J	CRYSTAL STRUCTURE OF THE XTCF3-CBD/BETA-CATENIN ARMADILLO REPEAT COMPLEX 分子名称: BETA-CATENIN ARMADILLO REPEAT REGION, TCF3-CBD (CATENIN BINDING DOMAIN) 著者 Graham, T.A, Weaver, C, Mao, F, Kimelman, D, Xu, W. 登録日 2000-10-24 公開日 2000-12-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a beta-catenin/Tcf complex. Cell(Cambridge,Mass.), 103, 2000
1JDH	CRYSTAL STRUCTURE OF BETA-CATENIN AND HTCF-4 分子名称: BETA-CATENIN, hTcf-4 著者 Graham, T.A, Ferkey, D.M, Mao, F, Kimelman, D, Xu, W. 登録日 2001-06-13 公開日 2001-12-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Tcf4 can specifically recognize beta-catenin using alternative conformations. Nat.Struct.Biol., 8, 2001
1JPW	Crystal Structure of a Human Tcf-4 / beta-Catenin Complex 分子名称: BETA-CATENIN, transcription factor 7-like 2 著者 Poy, F, Lepourcelet, M, Shivdasani, R.A, Eck, M.J. 登録日 2001-08-03 公開日 2001-12-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a human Tcf4-beta-catenin complex. Nat.Struct.Biol., 8, 2001
3TT9	Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant 分子名称: GLYCEROL, Plakophilin-2 著者 Schuetz, A, Roske, Y, Gerull, B, Heinemann, U. 登録日 2011-09-14 公開日 2012-08-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Circ Cardiovasc Genet, 5, 2012
3SLA	X-ray structure of first four repeats of human beta-catenin 分子名称: Catenin beta-1, GLYCEROL, SODIUM ION 著者 Gupta, D, Bienz, M. 登録日 2011-06-24 公開日 2012-02-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nat Commun, 3, 2012
4R0Z	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo 分子名称: FORMIC ACID, Protein humpback-2 著者 Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. 登録日 2014-08-03 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
1Y2A	Structure of mammalian importin bound to the non-classical PLSCR1-NLS 分子名称: Importin alpha-2 Subunit, decamer fragment of Phospholipid scramblase 1 著者 Chen, M.-H, Ben-Efraim, I, Mitrousis, G, Walker-Kopp, N, Sims, P.J, Cingolani, G. 登録日 2004-11-22 公開日 2005-02-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha J.Biol.Chem., 280, 2005
4HTV	Mouse importin alpha: BFDV Cap NLS peptide complex 分子名称: Importin subunit alpha-2, capsid protein 著者 Patterson, E.I, Forwood, J.K, Raidal, S.R. 登録日 2012-11-01 公開日 2012-11-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Mouse importin alpha: BFDV Cap NLS peptide complex TO BE PUBLISHED
4WV6	Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8 分子名称: 1,2-ETHANEDIOL, Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8 著者 Trowitzsch, S. 登録日 2014-11-04 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun, 6, 2015
2JDQ	C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 分子名称: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S. 登録日 2007-01-11 公開日 2007-02-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit Nat.Struct.Mol.Biol., 14, 2007
2GL7	Crystal Structure of a beta-catenin/BCL9/Tcf4 complex 分子名称: B-cell lymphoma 9 protein, Beta-catenin, Transcription factor 7-like 2 著者 Sampietro, J. 登録日 2006-04-04 公開日 2006-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of a beta-Catenin/BCL9/Tcf4 Complex. Mol.Cell, 24, 2006
5EKF	Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1 分子名称: DNA repair protein complementing XP-G cells, Importin subunit alpha-1 著者 Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. 登録日 2015-11-03 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428, 2016
5EKG	Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 2 分子名称: Importin subunit alpha-1, XPG2 peptide 著者 Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. 登録日 2015-11-03 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428, 2016
5W41	Zika MR766 NLS in complex with Importin alpha subunit-1 分子名称: Importin subunit alpha-1, ZIKA MR766 NLS 著者 Jeffress, S, Smith, K.M, Forwood, J.K. 登録日 2017-06-08 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells. ACS Infect Dis, 2019
5W4E	Importin binding to Tdt NLS peptide 分子名称: GLYCEROL, Importin subunit alpha-1,Importin subunit alpha-1, human DNA repair polymerase Tdt 著者 Pedersen, L.C, London, R. 登録日 2017-06-10 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
6D7N	Crystal structure of the W357R/W399R Importin alpha mutant 分子名称: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1 著者 Pedersen, L.C, London, R.E, Gabel, S.A. 登録日 2018-04-25 公開日 2019-03-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
6D7M	Crystal structure of the W184R/W231R Importin alpha mutant 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ... 著者 Pedersen, L.C, London, R.E, Gabel, S.A. 登録日 2018-04-25 公開日 2019-03-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.187 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
6P6E	Structure of Mouse Importin alpha - PAC3 NLS peptide complex 分子名称: Importin subunit alpha-1, PAC3 NLS 著者 Bernardes, N.E, Silva, T.D, Fukuda, C.A, Oliveira, H.C, Fontes, M.R.M. 登録日 2019-06-03 公開日 2020-01-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha. Sci Rep, 10, 2020

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