4U5W
| Crystal Structure of HIV-1 Nef-SF2 Core Domain in Complex with the Src Family Kinase Hck SH3-SH2 Tandem Regulatory Domains | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Protein Nef, ... | 著者 | Alvarado, J.J, Yeh, J.I, Smithgall, T.E. | 登録日 | 2014-07-25 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment. J.Biol.Chem., 289, 2014
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4ORZ
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4NEE
| crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit sigma, Protein Nef | 著者 | Hurley, J.H, Bonifacino, J.S, Ren, X, Park, S.Y. | 登録日 | 2013-10-29 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8841 Å) | 主引用文献 | How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. Elife, 3, 2014
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4EN2
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4EMZ
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4D8D
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3TB8
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3REB
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3REA
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3RBB
| HIV-1 NEF protein in complex with engineered HCK SH3 domain | 分子名称: | 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK | 著者 | Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M. | 登録日 | 2011-03-29 | 公開日 | 2011-04-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly. Traffic, 12, 2011
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3IOZ
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3IK5
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2XI1
| Crystal structure of the HIV-1 Nef sequenced from a patient's sample | 分子名称: | NEF | 著者 | Yadav, G.P, Singh, P, Gupta, S, Tripathi, A.K, Tripathi, R.K, Ramachandran, R. | 登録日 | 2010-06-25 | 公開日 | 2011-08-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef. Plos One, 6, 2011
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2NEF
| HIV-1 NEF (REGULATORY FACTOR), NMR, 40 STRUCTURES | 分子名称: | NEGATIVE FACTOR (F-PROTEIN) | 著者 | Grzesiek, S, Bax, A, Clore, G.M, Gronenborn, A.M, Hu, J.S, Kaufman, J, Palmer, I, Stahl, S.J, Tjandra, N, Wingfield, P.T. | 登録日 | 1997-02-12 | 公開日 | 1997-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Refined solution structure and backbone dynamics of HIV-1 Nef. Protein Sci., 6, 1997
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1EFN
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1AVZ
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1AVV
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