PDB: 104 件ウェブページステータス検索Chemie searchBIRD

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8E67	ETV6 H396Y variant bound to DNA containing the sequence GGAT 分子名称: Complementary 15 bp strand, GGAT-containing 15 bp DNA, Transcription factor ETV6 著者 Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P. 登録日 2022-08-22 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The functional role of histidine within the ETV6 ETS domain to be published
8E66	ETV6 H396Y variant bound to DNA containing the sequence GGAA 分子名称: CACODYLATE ION, Complementary 15 bp strand, GGAA-containing 15 bp DNA, ... 著者 Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P. 登録日 2022-08-22 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The functional role of histidine within the ETV6 ETS domain to be published
8E5Y	Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E4H	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-18 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3R	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-17 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3K	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-17 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8BZM	FOXK1-ELF1-heterodimer bound to DNA 分子名称: DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ... 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2022-12-15 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 FOXK1-ELF1_heterodimer bound to DNA To Be Published
7JSL	Crystal structure of the DNA binding domain of human transcription factor ERF in the oxidized form, in complex with double-stranded DNA ACCGGAAGTG 分子名称: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF 著者 Hou, C, Tsodikov, O.V. 登録日 2020-08-14 公開日 2020-11-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.51 Å) 主引用文献 Structural Insight into the DNA Binding Function of Transcription Factor ERF. Biochemistry, 2020
7JSA	Crystal structure of the DNA binding domain of human transcription factor ERF in the reduced form, in complex with double-stranded DNA ACCGGAAGTG 分子名称: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF 著者 Hou, C, Tsodikov, O.V. 登録日 2020-08-14 公開日 2020-11-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural Insight into the DNA Binding Function of Transcription Factor ERF. Biochemistry, 2020
6VGG	Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Rohr, J, Tsodikov, O.V. 登録日 2020-01-08 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VGE	Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.25 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VGD	Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human Runx2 with core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VG8	Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with 16-mer DNA CAGAGGATGTGGCTTC 分子名称: DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VG2	Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with 16-mer DNA CAGAGGATGTGGCTTC 分子名称: DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*CP*TP*TP*C)-3'), Friend leukemia integration 1 transcription factor 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6DAT	ETS1 in complex with synthetic SRR mimic 分子名称: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide 著者 Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P. 登録日 2018-05-02 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35002637 Å) 主引用文献 The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J. Mol. Biol., 431, 2019
6DA1	ETS1 in complex with synthetic SRR mimic 分子名称: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide 著者 Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P. 登録日 2018-05-01 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.000127 Å) 主引用文献 The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J. Mol. Biol., 431, 2019
5ZMC	Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 分子名称: DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ... 著者 Xu, X, Bharath, S.R, Song, H. 登録日 2018-04-02 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1. Nat Commun, 9, 2018
5YBD	X-ray structure of ETS domain of Ergp55 in complex with E74DNA 分子名称: DNA (5'-D(P*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), Transcriptional regulator ERG 著者 Saxena, A.K, Gangwar, S.P. 登録日 2017-09-04 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.769 Å) 主引用文献 Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence Acta Crystallogr F Struct Biol Commun, 74, 2018
5YBC	X-ray structure of native ETS-domain domain of Ergp55 分子名称: GLYCEROL, Transcriptional regulator ERG 著者 Saxena, A.K, Gangwar, S.P. 登録日 2017-09-04 公開日 2018-09-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence Acta Crystallogr F Struct Biol Commun, 74, 2018
5W3G	Solution Structure of ETS Transcription Factor PU.1 分子名称: Transcription factor PU.1 著者 Lau, D.K.W, Okon, M, McIntosh, L.P. 登録日 2017-06-07 公開日 2018-06-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Conserved protein dynamics within the ETS transcription factor family To be published
5JVT	Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer DNA GACCGGAAGTG 分子名称: DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ... 著者 Hou, C, Tsodikov, O.V. 登録日 2016-05-11 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
5ILV	Uninhibited ETV5 分子名称: ETS translocation variant 5 著者 Whitby, F.G, Currie, S.L. 登録日 2016-03-04 公開日 2017-02-22 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
5ILU	Autoinhibited ETV4 分子名称: ETS translocation variant 4 著者 Whitby, F.G, Currie, S.L. 登録日 2016-03-04 公開日 2017-02-22 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.101 Å) 主引用文献 Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
5ILS	Autoinhibited ETV1 分子名称: ETS translocation variant 1 著者 Whitby, F.G, Currie, S.L. 登録日 2016-03-04 公開日 2017-02-22 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
5E8I	Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a 10-mer DNA ACCGGAAGTG 分子名称: CALCIUM ION, DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ... 著者 Hou, C, Tsodikov, O.V. 登録日 2015-10-14 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1. Biochemistry, 54, 2015

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