5E8I
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a 10-mer DNA ACCGGAAGTG
Summary for 5E8I
Entry DOI | 10.2210/pdb5e8i/pdb |
Related | 5E8G |
Descriptor | Friend leukemia integration 1 transcription factor, DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ... (5 entities in total) |
Functional Keywords | transcription, dna binding, ewing sarcoma, winged helix, ets family, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q01543 |
Total number of polymer chains | 12 |
Total formula weight | 84467.98 |
Authors | Hou, C.,Tsodikov, O.V. (deposition date: 2015-10-14, release date: 2015-12-09, Last modification date: 2023-09-27) |
Primary citation | Hou, C.,Tsodikov, O.V. Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1. Biochemistry, 54:7365-7374, 2015 Cited by PubMed: 26618620DOI: 10.1021/acs.biochem.5b01121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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