5E8I
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a 10-mer DNA ACCGGAAGTG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, G, J | Friend leukemia integration 1 transcription factor | polymer | 128 | 14946.8 | 4 | UniProt (Q01543) Pfam (PF00178) In PDB | Homo sapiens (Human) | Proto-oncogene Fli-1,Transcription factor ERGB |
2 | B, E, H, K | DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3') | polymer | 10 | 3094.0 | 4 | Endothia gyrosa | ||
3 | C, F, I, L | DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3') | polymer | 10 | 2996.0 | 4 | Endothia gyrosa | ||
4 | B, C, F, H, I... | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
5 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 276 - 399 (UniProt: Q01543)
PDB | External Database | Details |
---|---|---|
Gly 272 | - | expression tag |
Pro 273 | - | expression tag |
His 274 | - | expression tag |
Met 275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 84147.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 320.6 | |
All* | Total formula weight | 84468.0 |