5E8I
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a 10-mer DNA ACCGGAAGTG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | Friend leukemia integration 1 transcription factor | polymer | 128 | 14946.8 | 4 | UniProt (Q01543) Pfam (PF00178) | Homo sapiens (Human) | Proto-oncogene Fli-1,Transcription factor ERGB |
| 2 | B, E, H, K (B, E, H, K) | DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3') | polymer | 10 | 3094.0 | 4 | Endothia gyrosa | ||
| 3 | C, F, I, L (C, F, I, L) | DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3') | polymer | 10 | 2996.0 | 4 | Endothia gyrosa | ||
| 4 | M, N, O, P, Q... (B, C, F, H, I...) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | U, V, W (A, G, J) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 276 - 399 (UniProt: Q01543)
| PDB | External Database | Details |
|---|---|---|
| Gly 272 | - | expression tag |
| Pro 273 | - | expression tag |
| His 274 | - | expression tag |
| Met 275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 84147.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 320.6 | |
| All* | Total formula weight | 84468.0 |
