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1EIE
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CRYSTAL STRUCTURE OF F120W MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-02-25
公開日2002-02-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1EID
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BU of 1eid by Molmil
CRYSTAL STRUCTURE OF F120G MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-02-25
公開日2002-02-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1EOW
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BU of 1eow by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE A COMPLEXED WITH URIDYLYL(2',5')GUANOSINE (NON-PRODUCTIVE BINDING)
分子名称: RIBONUCLEASE PANCREATIC, SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE
著者Vitagliano, L, Merlino, A, Zagari, A, Mazzarella, L.
登録日2000-03-24
公開日2000-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2',5')guanosine.
Protein Sci., 9, 2000
7P4R
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BU of 7p4r by Molmil
Ultra High Resolution X-ray Structure of Orthorhombic Bovine Pancreatic Ribonuclease at 100K
分子名称: ETHANOL, Ribonuclease pancreatic, SULFATE ION
著者Lisgarten, D.R, Palmer, R.A, Cooper, J.B, Naylor, C.E, Howlin, B.J, Lisgarten, J.N, Najmudin, S, Lobley, C.M.C.
登録日2021-07-12
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K.
BMC Chem, 17, 2023
1EIC
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BU of 1eic by Molmil
CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-02-25
公開日2002-02-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
7PNJ
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BU of 7pnj by Molmil
Human Angiogenin quardruple mutant-S28AT36AS37AS87A
分子名称: Angiogenin, CITRIC ACID
著者Papaioannou, O.S.E, Leonidas, D.D.
登録日2021-09-07
公開日2021-09-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and Biochemical Characterization of the Human Angiogenin-Proliferating Cell Nuclear Antigen Interaction.
Biochemistry, 62, 2023
7PNR
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BU of 7pnr by Molmil
Human Angiogenin mutant-S28AT36AS37A
分子名称: Angiogenin
著者Papaioannou, O.S.E, Leonidas, D.D.
登録日2021-09-07
公開日2021-09-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Biochemical Characterization of the Human Angiogenin-Proliferating Cell Nuclear Antigen Interaction.
Biochemistry, 62, 2023
7PNI
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BU of 7pni by Molmil
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with ribonuclease A
分子名称: PLATINUM (II) ION, Ribonuclease pancreatic
著者Ferraro, G, Merlino, A.
登録日2021-09-07
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Reactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands.
Int J Mol Sci, 22, 2021
8F5X
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BU of 8f5x by Molmil
Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP)
分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Non-secretory ribonuclease, ...
著者Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N.
登録日2022-11-15
公開日2023-11-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.
J.Biol.Chem., 300, 2024
7NPM
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X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin
分子名称: Angiogenin, D(-)-TARTARIC ACID, PLATINUM (II) ION
著者Ferraro, G, Merlino, A.
登録日2021-02-27
公開日2022-03-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells.
J.Inorg.Biochem., 226, 2022
8FHM
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RNase A-Uridine 5'-Hexaphosphate (RNaseA.p6U)
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine, Ribonuclease pancreatic
著者Park, G, Cummins, C.
登録日2022-12-14
公開日2023-12-20
最終更新日2024-08-07
実験手法SOLUTION SCATTERING (1.79 Å), X-RAY DIFFRACTION
主引用文献Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A.
Acs Cent.Sci., 10, 2024
7OR6
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BU of 7or6 by Molmil
The crystal structure of the domain-swapped dimer of onconase
分子名称: Protein P-30
著者Merlino, A, Loreto, D.
登録日2021-06-04
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
7ORD
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BU of 7ord by Molmil
The crystal structure of the domain-swapped dimer of onconase (2)
分子名称: ACETATE ION, Protein P-30, SULFATE ION
著者Merlino, A, Loreto, D.
登録日2021-06-05
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
7P8R
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BU of 7p8r by Molmil
X-ray structure of the adduct of a vanadium picolinate complex with RNase A at pH 5.1
分子名称: Ribonuclease pancreatic, SULFATE ION, hydroxy(oxo)bis(pyridine-2-carboxylato-kappa~2~N,O)vanadium(3+)
著者Ferraro, G, Merlino, A.
登録日2021-07-23
公開日2021-12-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Spectroscopic/Computational Characterization and the X-ray Structure of the Adduct of the V IV O-Picolinato Complex with RNase A.
Inorg.Chem., 60, 2021
8GGG
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BU of 8ggg by Molmil
RNase A-Adenosine 5'-Hexaphosphate (RNaseA.p6A)
分子名称: GLYCEROL, Ribonuclease pancreatic, adenosine 5'-hexaphosphate
著者Park, G, Cummins, C.
登録日2023-03-08
公開日2024-03-13
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A.
Acs Cent.Sci., 10, 2024
8GC9
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BU of 8gc9 by Molmil
RNase A-Uridine 5'-Heptaphosphate (RNase A.p7U)
分子名称: Ribonuclease pancreatic, uridine 5'-heptaphosphate
著者Park, G, Cummins, C.
登録日2023-03-01
公開日2024-03-06
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A.
Acs Cent.Sci., 10, 2024
5E13
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BU of 5e13 by Molmil
Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c
分子名称: 3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine, Non-secretory ribonuclease
著者Chatzileontiadou, D.S.M, Stravodimos, G.A, Kantsadi, A.L, Leonidas, D.D.
登録日2015-09-29
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.
Bioorg.Chem., 63, 2015
5EPZ
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BU of 5epz by Molmil
Human Angiogenin in complex with sulphate anions at a basic solution
分子名称: Angiogenin, GLYCEROL, SULFATE ION
著者Chatzileontiadou, D.S.M, Leonidas, D.D.
登録日2015-11-12
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5EOP
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Crystal structure of human Angiogenin at 1.35 Angstroms resolution
分子名称: Angiogenin
著者Chatzileontiadou, D.S.M, Tsirkone, V.G, Dossi, K, Leonidas, D.D.
登録日2015-11-10
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5OAB
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BU of 5oab by Molmil
A novel crystal form of human RNase6 at atomic resolution
分子名称: CHLORIDE ION, PHOSPHATE ION, POTASSIUM ION, ...
著者Prats-Ejarque, G, Moussaoui, M, Boix, E.
登録日2017-06-21
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.111 Å)
主引用文献Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
5ET4
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BU of 5et4 by Molmil
Structure of RNase A-K7H/R10H in complex with 3'-CMP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-3'-MONOPHOSPHATE, Ribonuclease pancreatic
著者Blanco, J.A, Salazar, V.A, Moussaoui, M, Boix, E.
登録日2015-11-17
公開日2016-11-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
6PVU
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BU of 6pvu by Molmil
RNase A in complex with hexametaphosphate
分子名称: 2,4,6,8,10,12-hexahydroxy-2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~,10lambda~5~,12lambda~5~-cyclohexaphosphoxane-2,4,6,8,10,12-hexone, Ribonuclease pancreatic
著者Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T.
登録日2019-07-21
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019
6PVW
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RNase A in complex with cp4pA
分子名称: 2,4,6,8-tetrahydroxy-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetroxatetraphosphocane-2,4,6,8-tetrone, 5'-O-[(R)-hydroxy{[(4R,8S)-4,6,8-trihydroxy-2,4,6,8-tetraoxo-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetroxatetraphosphocan-2-yl]oxy}phosphoryl]adenosine, Ribonuclease pancreatic
著者Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T.
登録日2019-07-21
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019
5OBC
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X-ray structure of the adduct formed upon reaction of ribonuclease A with the compound fac-[RuII(CO)3Cl2(N3-IM), IM=imidazole
分子名称: PHOSPHATE ION, Ribonuclease pancreatic, pentakis(oxidaniumyl)-(oxidaniumylidynemethyl)ruthenium, ...
著者Pontillo, N, Ferraro, G, Merlino, A.
登録日2017-06-26
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Ru-Based CO releasing molecules with azole ligands: interaction with proteins and the CO release mechanism disclosed by X-ray crystallography.
Dalton Trans, 46, 2017
6PVX
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RNase A in complex with p5U
分子名称: 5'-O-[(R)-hydroxy{[(S)-hydroxy{[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine, Ribonuclease pancreatic
著者Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T.
登録日2019-07-21
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J.Am.Chem.Soc., 141, 2019

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