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8FHM

RNase A-Uridine 5'-Hexaphosphate (RNaseA.p6U)

Summary for 8FHM
Entry DOI10.2210/pdb8fhm/pdb
DescriptorRibonuclease pancreatic, 5'-O-[(S)-hydroxy{[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine (3 entities in total)
Functional Keywordsrnase a, oligophosphate, inhibitor, nucleoside hexaphosphate, protein-ligan complex, rna binding protein-inhibitor complex, rna binding protein/inhibitor
Biological sourceBos taurus (cattle)
Total number of polymer chains2
Total formula weight29588.89
Authors
Park, G.,Cummins, C. (deposition date: 2022-12-14, release date: 2023-12-20, Last modification date: 2024-07-24)
Primary citationPark, G.,Wralstad, E.C.,Faginas-Lago, N.,Qian, K.,Raines, R.T.,Bistoni, G.,Cummins, C.C.
Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A
Acs Cent.Sci., 2024
Cited by
DOI: 10.1021/acscentsci.4c00835
PDB entries with the same primary citation
Experimental method
SOLUTION SCATTERING
X-RAY DIFFRACTION (1.79 Å)
Structure validation

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PDB entries from 2024-07-31

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