8FHM
RNase A-Uridine 5'-Hexaphosphate (RNaseA.p6U)
Summary for 8FHM
Entry DOI | 10.2210/pdb8fhm/pdb |
Descriptor | Ribonuclease pancreatic, 5'-O-[(S)-hydroxy{[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine (3 entities in total) |
Functional Keywords | rnase a, oligophosphate, inhibitor, nucleoside hexaphosphate, protein-ligan complex, rna binding protein-inhibitor complex, rna binding protein/inhibitor |
Biological source | Bos taurus (cattle) |
Total number of polymer chains | 2 |
Total formula weight | 29588.89 |
Authors | Park, G.,Cummins, C. (deposition date: 2022-12-14, release date: 2023-12-20, Last modification date: 2024-07-24) |
Primary citation | Park, G.,Wralstad, E.C.,Faginas-Lago, N.,Qian, K.,Raines, R.T.,Bistoni, G.,Cummins, C.C. Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A Acs Cent.Sci., 2024 Cited by DOI: 10.1021/acscentsci.4c00835PDB entries with the same primary citation |
Experimental method | SOLUTION SCATTERING X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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