PDB: 197 件ウェブページステータス検索Chemie searchBIRD

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5XX8	Hetero-micro-seeding: Crystal structure of BPTI-[555]C14GA38I variant using micro-seeds from -C14GA38L variant 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 A hetero-micro-seeding strategy for readily crystallizing closely related protein variants Biochem. Biophys. Res. Commun., 493, 2017
5XX7	Hetero-micro-seeding: Crystal structure of BPTI-[5,55]C14GA38I variant using micro-seeds from -C14GA38I variant 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 A hetero-micro-seeding strategy for readily crystallizing closely related protein variants Biochem. Biophys. Res. Commun., 493, 2017
5XX6	Hetero-micro-seeding: Crystal structure of BPTI-[5,55]C14GA38I variant using micro-seeds from -C14GA38G variant 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 A hetero-micro-seeding strategy for readily crystallizing closely related protein variants Biochem. Biophys. Res. Commun., 493, 2017
5XX5	A BPTI-[5,55] variant with C14GA38I mutations 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Hydrophobic surface residues can stabilize a protein through improved water-protein interactions. Febs J., 2019
5XX4	A BPTI-[5,55] variant with C14GA38K mutations 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Hydrophobic surface residues can stabilize a protein through improved water-protein interactions. Febs J., 2019
5XX3	A BPTI-[5,55] variant with C14GA38G mutations 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Hydrophobic surface residues can stabilize a protein through improved water-protein interactions. Febs J., 2019
5XX2	A BPTI-[5,55] variant with C14GA38L mutations 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2017-07-01 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Hydrophobic surface residues can stabilize a protein through improved water-protein interactions. Febs J., 2019
5PTI	STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT OF CRYSTAL FORM II 分子名称: PHOSPHATE ION, TRYPSIN INHIBITOR, UNKNOWN ATOM OR ION 著者 Wlodawer, A, Huber, R. 登録日 1984-10-05 公開日 1984-10-29 最終更新日 2018-10-24 実験手法 NEUTRON DIFFRACTION (1 Å), X-RAY DIFFRACTION 主引用文献 Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II J.Mol.Biol., 180, 1984
5NX3	Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy 分子名称: Amyloid-beta A4 protein, Kallikrein-6 著者 Shahar, A, Sananes, A, Radisky, E.S, Papo, N. 登録日 2017-05-09 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.296 Å) 主引用文献 A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering. J.Biol.Chem., 293, 2018
5NX1	Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy 分子名称: Amyloid-beta A4 protein, Kallikrein-6 著者 Shahar, A, Sananes, A, Radisky, E.S, Papo, N. 登録日 2017-05-09 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering. J.Biol.Chem., 293, 2018
5NMV	Crystal structure of 2F22 Fab fragment against TFPI1 分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ... 著者 Svensson, L.A, Petersen, H.H. 登録日 2017-04-07 公開日 2018-03-28 最終更新日 2018-05-09 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Factor Xa and VIIa inhibition by tissue factor pathway inhibitor is prevented by a monoclonal antibody to its Kunitz-1 domain. J. Thromb. Haemost., 16, 2018
5M4V	X-ray structure of the mambaquaretin-1, a selective antagonist of the vasopressin type 2 receptor 分子名称: CHLORIDE ION, Mambaquaretin-1, S-1,2-PROPANEDIOL 著者 Stura, E.A, Vera, L, Ciolek, J, Mourier, G, Gilles, N. 登録日 2016-10-19 公開日 2017-05-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5JBT	Mesotrypsin in complex with cleaved amyloid precursor like protein 2 inhibitor (APLP2) 分子名称: Amyloid-like protein 2, CALCIUM ION, PRSS3 protein, ... 著者 Kayode, O, Wang, R, Pendlebury, D, Soares, A, Radisky, E.S. 登録日 2016-04-13 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis. J. Biol. Chem., 291, 2016
5JB7	A simplified BPTI variant containing 24 alanines out of 58 residues 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2016-04-13 公開日 2017-04-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy Sci Rep, 7, 2017
5JB6	A simplified BPTI variant containing 23 alanines out of 58 residues 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2016-04-13 公開日 2017-04-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy Sci Rep, 7, 2017
5JB5	A simplified BPTI variant containing 22 alanines out of 58 residues 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2016-04-13 公開日 2017-04-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy Sci Rep, 7, 2017
5JB4	A simplified BPTI variant containing 21 alanines out 58 of residues 分子名称: Pancreatic trypsin inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2016-04-13 公開日 2017-04-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy Sci Rep, 7, 2017
5H7V	Structure of full-length extracellular domain of HAI-1 at pH 4.6 分子名称: Kunitz-type protease inhibitor 1 著者 Liu, M, Huang, M. 登録日 2016-11-21 公開日 2017-03-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.82 Å) 主引用文献 The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition J. Biol. Chem., 292, 2017
5EZD	Crystal structure of a Hepatocyte growth factor activator inhibitor-1 (HAI-1) fragment covering the PKD-like 'internal' domain and Kunitz domain 1 分子名称: ACETATE ION, Kunitz-type protease inhibitor 1, POTASSIUM ION 著者 Hong, Z, Andreasen, P.A, Morth, J.P, Jensen, J.K. 登録日 2015-11-26 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN. J.Biol.Chem., 291, 2016
5C67	Human Mesotrypsin in complex with amyloid precursor protein inhibitor variant APPI-M17G/I18F/F34V 分子名称: Amyloid beta A4 protein, Trypsin-3 著者 Kayode, O, Sankaran, B, Radisky, E.S. 登録日 2015-06-22 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy. Biochem.J., 473, 2016
4Y11	Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4,4-trifluorobutanoic acid 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. 登録日 2015-02-06 公開日 2015-06-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
4Y10	Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4-difluorobutanoic acid 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. 登録日 2015-02-06 公開日 2015-06-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
4Y0Z	Trypsin in complex with with BPTI mutant AMINOBUTYRIC ACID 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. 登録日 2015-02-06 公開日 2015-06-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
4Y0Y	Trypsin in complex with with BPTI 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. 登録日 2015-02-06 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
4WXV	Human cationic trypsin K97D mutant in complex with bovine pancreatic trypsin inhibitor (BPTI) 分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ... 著者 Alloy, A, Kayode, O, Soares, A.S, Wang, R, Radisky, E.S. 登録日 2014-11-14 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. J.Biol.Chem., 290, 2015

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