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2MUM
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Solution structure of the PHD domain of Yeast YNG2
分子名称: Chromatin modification-related protein YNG2, ZINC ION
著者Taeb, S, Kaustov, L, Lemak, A, Farhadi, S, Sheng, Y.
登録日2014-09-12
公開日2014-12-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the PHD domain of Yeast YNG2
To be Published
2NS2
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Crystal Structure of Spindlin1
分子名称: PHOSPHATE ION, Spindlin-1
著者Zhao, Q, Qin, L, Jiang, F, Wu, B, Yue, W, Xu, F, Rong, Z, Yuan, H, Xie, X, Gao, Y, Bai, C, Bartlam, M.
登録日2006-11-02
公開日2006-11-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation
J.Biol.Chem., 282, 2007
2PNX
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The PHD finger of ING4 in complex with an H3K4Me3 histone peptide
分子名称: H3K4Me3 peptide, Inhibitor of growth protein 4, ZINC ION
著者Champagne, K.S, Johnson, K, Kutateladze, T.G.
登録日2007-04-25
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
Mol.Cell, 33, 2009
2PUY
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Crystal Structure of the BHC80 PHD finger
分子名称: Histone H3, PHD finger protein 21A, ZINC ION
著者Horton, J.R, Cheng, X, Collins, R.E.
登録日2007-05-09
公開日2007-08-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
Nature, 448, 2007
2QIC
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Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide
分子名称: H3K4ME3 PEPTIDE, Inhibitor of growth protein 1, ZINC ION
著者Pena, P.V, Champagne, K, Zhao, R, Kutateladze, T.G.
登録日2007-07-03
公開日2008-05-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
J.Mol.Biol., 380, 2008
2QQR
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JMJD2A hybrid tudor domains
分子名称: JmjC domain-containing histone demethylation protein 3A, SULFATE ION
著者Lee, J, Botuyan, M.V, Mer, G.
登録日2007-07-26
公開日2007-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
2QQS
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JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide
分子名称: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE
著者Lee, J, Botuyan, M.V, Mer, G.
登録日2007-07-26
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
2RR4
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Complex structure of the zf-CW domain and the H3K4me3 peptide
分子名称: Histone H3, ZINC ION, Zinc finger CW-type PWWP domain protein 1
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2010-03-24
公開日2010-09-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insight into the zinc finger CW domain as a histone modification reader
Structure, 18, 2010
2RSD
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Solution structure of the plant homeodomain (PHD) of the E3 SUMO ligase Siz1 from rice
分子名称: E3 SUMO-protein ligase SIZ1, ZINC ION
著者Shindo, H, Tsuchiya, W, Suzuki, R, Yamazaki, T.
登録日2012-01-12
公開日2012-08-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2
Febs Lett., 586, 2012
2V83
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V85
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Crystal structure of RAG2-PHD finger in complex with H3R2me1K4me3 peptide
分子名称: H3R2ME1K4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V86
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Crystal structure of RAG2-PHD finger in complex with H3R2me2aK4me3 peptide
分子名称: H3R2ME2AK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V87
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Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me3 peptide
分子名称: HISTONE H3.2, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V88
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Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me2 peptide
分子名称: H3R2ME2SK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V89
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Rag2 Phd Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination.
Nature, 450, 2007
2VNF
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MOLECULAR BASIS OF HISTONE H3K4ME3 RECOGNITION BY ING4
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, HISTONE H3, ...
著者Palacios, A, Munoz, I.G, Pantoja-Uceda, D, Marcaida, M.J, Torres, D, Martin-Garcia, J.M, Luque, I, Montoya, G, Blanco, F.J.
登録日2008-02-04
公開日2008-04-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Molecular Basis of Histone H3K4Me3 Recognition by Ing4
J.Biol.Chem., 283, 2008
2XAF
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Crystal structure of LSD1-CoREST in complex with para-bromo-(+)-cis-2- phenylcyclopropyl-1-amine
分子名称: 3-(4-BROMOPHENYL)PROPANAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAG
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Crystal structure of LSD1-CoREST in complex with para-bromo-(-)-trans- 2-phenylcyclopropyl-1-amine
分子名称: 3-(4-BROMOPHENYL)PROPANAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAH
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Crystal structure of LSD1-CoREST in complex with (+)-trans-2- phenylcyclopropyl-1-amine
分子名称: 3-PHENYLPROPANAL, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAJ
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Crystal structure of LSD1-CoREST in complex with (-)-trans-2- phenylcyclopropyl-1-amine
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, PHENYLETHYLENECARBOXYLIC ACID, ...
著者Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAQ
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Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2584, 13b)
分子名称: 3-{4-[(PHENYLCARBONYL)AMINO]PHENYL}PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAS
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Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2580, 14e)
分子名称: 3-[4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)PHENYL]PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2YB8
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Crystal structure of Nurf55 in complex with Su(z)12
分子名称: POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
2YBA
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Crystal structure of Nurf55 in complex with histone H3
分子名称: HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
2YYR
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Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide
分子名称: H3K4Me3 peptide, Pygopus homolog 1, ZINC ION
著者Nakamura, Y, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-01
公開日2008-05-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide
To be Published

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