2PNX

The PHD finger of ING4 in complex with an H3K4Me3 histone peptide

Summary for 2PNX

• Entry DOI: 10.2210/pdb2pnx/pdb
• Descriptor: Inhibitor of growth protein 4, H3K4Me3 peptide, ZINC ION, ... (4 entities in total)
• Functional Keywords: protein-peptide complex, chromatin, zinc finger, histone, gene regulation
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9UNL4
• Total number of polymer chains: 4
• Total formula weight: 15555.05

Authors

Champagne, K.S.,Johnson, K.,Kutateladze, T.G. (deposition date: 2007-04-25, release date: 2008-04-15, Last modification date: 2011-07-13)

• Primary citation: Hung, T.,Binda, O.,Champagne, K.S.,Kuo, A.J.,Johnson, K.,Chang, H.Y.,Simon, M.D.,Kutateladze, T.G.,Gozani, O.; ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation; Mol.Cell, 33:248-256, 2009; PubMed: 19187765; DOI: 10.1016/j.molcel.2008.12.016

Experimental method

X-RAY DIFFRACTION (1.8 Å)