2PNX
The PHD finger of ING4 in complex with an H3K4Me3 histone peptide
Summary for 2PNX
Entry DOI | 10.2210/pdb2pnx/pdb |
Descriptor | Inhibitor of growth protein 4, H3K4Me3 peptide, ZINC ION, ... (4 entities in total) |
Functional Keywords | protein-peptide complex, chromatin, zinc finger, histone, gene regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9UNL4 |
Total number of polymer chains | 4 |
Total formula weight | 15555.05 |
Authors | Champagne, K.S.,Johnson, K.,Kutateladze, T.G. (deposition date: 2007-04-25, release date: 2008-04-15, Last modification date: 2011-07-13) |
Primary citation | Hung, T.,Binda, O.,Champagne, K.S.,Kuo, A.J.,Johnson, K.,Chang, H.Y.,Simon, M.D.,Kutateladze, T.G.,Gozani, O. ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation Mol.Cell, 33:248-256, 2009 Cited by PubMed: 19187765DOI: 10.1016/j.molcel.2008.12.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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