2PNX

The PHD finger of ING4 in complex with an H3K4Me3 histone peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 300

Chain	Residue
A	CYS199
A	CYS201
A	HIS223
A	CYS226

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 400

Chain	Residue
A	CYS212
A	CYS217
A	CYS239
A	CYS242

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 300

Chain	Residue
C	CYS201
C	HIS223
C	CYS226
C	CYS199

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 400

Chain	Residue
C	CYS212
C	CYS217
C	CYS239
C	CYS242

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	44
Details	ZF_PHD_1 Zinc finger PHD-type signature. Cl.Chqvsygem.....................................IgCdnpdCsiewFHfaCvglttkprgk...................................WfCprC

Chain	Residue	Details
A	CYS199-CYS242

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	49
Details	Zinc finger: {"description":"PHD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9UK53","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Site: {"description":"Histone H3K4me3 binding","evidences":[{"source":"UniProtKB","id":"Q9UK53","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---