2PNX

The PHD finger of ING4 in complex with an H3K4Me3 histone peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 300

Chain	Residue
A	CYS199
A	CYS201
A	HIS223
A	CYS226

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 400

Chain	Residue
A	CYS212
A	CYS217
A	CYS239
A	CYS242

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 300

Chain	Residue
C	CYS201
C	HIS223
C	CYS226
C	CYS199

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 400

Chain	Residue
C	CYS212
C	CYS217
C	CYS239
C	CYS242

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	44
Details	ZF_PHD_1 Zinc finger PHD-type signature. Cl.Chqvsygem.....................................IgCdnpdCsiewFHfaCvglttkprgk...................................WfCprC

Chain	Residue	Details
A	CYS199-CYS242

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	98
Details	ZN_FING: PHD-type => ECO:0000255|PROSITE-ProRule:PRU00146

Chain	Residue	Details
A	PRO196-GLU245
C	PRO196-GLU245

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9UK53

Chain	Residue	Details
A	CYS199
C	CYS201
C	CYS212
C	CYS217
C	HIS223
C	CYS226
C	CYS239
C	CYS242
A	CYS201
A	CYS212
A	CYS217
A	HIS223
A	CYS226
A	CYS239
A	CYS242
C	CYS199

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Histone H3K4me3 binding => ECO:0000250|UniProtKB:Q9UK53

Chain	Residue	Details
A	TYR198
A	MET209
A	ASP213
A	TRP221
C	TYR198
C	MET209
C	ASP213
C	TRP221

---